Microglia Participate in Neurogenic Regulation of Hypertension

Hypertension is associated with neuroinflammation and increased sympathetic tone. Interference with neuroinflammation by an anti-inflammatory reagent or overexpression of interleukin-10 in the brain was found to attenuate hypertension. However, the cellular mechanism of neuroinflammation, as well as...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 2015-08, Vol.66 (2), p.309-316
Hauptverfasser:	Shen, Xiao Z, Li, You, Li, Liang, Shah, Kandarp H, Bernstein, Kenneth E, Lyden, Patrick, Shi, Peng
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II - adverse effects Animals Apoptosis - drug effects Blood Pressure - physiology Diphtheria Toxin - administration & dosage Diphtheria Toxin - pharmacology Disease Models, Animal Hypertension - chemically induced Hypertension - physiopathology Infusions, Intraventricular Mice Mice, Inbred C57BL Microglia - drug effects Microglia - physiology NG-Nitroarginine Methyl Ester - adverse effects Sympathetic Nervous System - physiology
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