Expression of MMP-1/PAR-1 and patterns of invasion in oral squamous cell carcinoma as potential prognostic markers

Matrix metalloproteinase (MMP)-1 degrades type I collagen of the extracellular matrix and also activates protease activated receptor (PAR)-1 to induce angiogenesis. The aims of this study were to evaluate microvessel density (MVD) and the expression of PAR-1 and MMP-1 in oral squamous cell carcinoma...

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Veröffentlicht in:OncoTargets and therapy 2015-01, Vol.8, p.1619-1626
Hauptverfasser: Fan, Hai-Xia, Chen, Yan, Ni, Bo-Xiong, Wang, Shan, Sun, Miao, Chen, Dong, Zheng, Jin-Hua
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Sprache:eng
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