PI3K/Akt/mTOR signaling pathway in cancer stem cells: from basic research to clinical application

Cancer stem cells (CSCs) are a subpopulation of tumor cells that possess unique self-renewal activity and mediate tumor initiation and propagation. The PI3K/Akt/mTOR signaling pathway can be considered as a master regulator for cancer. More and more recent studies have shown the links between PI3K/A...

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Veröffentlicht in:	American journal of cancer research 2015-01, Vol.5 (5), p.1602-1609
Hauptverfasser:	Xia, Pu, Xu, Xiao-Yan
Format:	Artikel
Sprache:	eng
Schlagworte:	Review
Online-Zugang:	Volltext
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