Cathepsin B-deficient mice as source of monoclonal anti-cathepsin B antibodies

Cathepsin B has been demonstrated to be involved in several proteolytic processes that support tumor progression and metastasis and neurodegeneration. To further clarify its role, defined monoclonal antibodies are needed. As the primary structure of human cathepsin B is almost identical to that of t...

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Veröffentlicht in:Biological chemistry 2015-03, Vol.396 (3), p.277-281
Hauptverfasser: Weber, Ekkehard, Barbulescu, Elena, Medek, Rita, Reinheckel, Thomas, Sameni, Mansoureh, Anbalagan, Arulselvi, Moin, Kamiar, Sloane, Bonnie F.
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Sprache:eng
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