Relation of Serum and Vitreous Concentrations of Fetuin-A with Diabetic Retinopathy
Fetuin-A, a liver-derived glycoprotein, is correlated with diabetes. The aim of the present investigation was to evaluate serum and vitreous concentrations of fetuin-A in patients with diabetic retinopathy (DR). We randomly selected 224 diabetic patients and 68 control subjects for this study. RESUL...
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| Veröffentlicht in: | Medical science monitor 2015-06, Vol.21, p.1839-1842 |
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| creator | Zhao, Chunming Hou, Jiangping Wang, Shengxi Jiang, Rui |
| description | Fetuin-A, a liver-derived glycoprotein, is correlated with diabetes. The aim of the present investigation was to evaluate serum and vitreous concentrations of fetuin-A in patients with diabetic retinopathy (DR).
We randomly selected 224 diabetic patients and 68 control subjects for this study. RESULTS :There were markedly higher serum and vitreous fetuin-A concentrations in proliferative diabetic retinopathy (PDR) patients than in the other three groups. NPDR patients exhibited elevated vitreous fetuin-A concentrations compared with patients without DR. However, no significant differences in serum fetuin-A concentrations were observed between NPDR patients and patients without DR. In addition, there were significantly lower concentrations of serum and vitreous fetuin-A in control subjects compared with the other three groups.
The occurrence and severity of DR is correlated with serum and vitreous fetuin-A concentrations. |
| doi_str_mv | 10.12659/MSM.893403 |
| format | Article |
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We randomly selected 224 diabetic patients and 68 control subjects for this study. RESULTS :There were markedly higher serum and vitreous fetuin-A concentrations in proliferative diabetic retinopathy (PDR) patients than in the other three groups. NPDR patients exhibited elevated vitreous fetuin-A concentrations compared with patients without DR. However, no significant differences in serum fetuin-A concentrations were observed between NPDR patients and patients without DR. In addition, there were significantly lower concentrations of serum and vitreous fetuin-A in control subjects compared with the other three groups.
The occurrence and severity of DR is correlated with serum and vitreous fetuin-A concentrations.</description><identifier>ISSN: 1643-3750</identifier><identifier>ISSN: 1234-1010</identifier><identifier>EISSN: 1643-3750</identifier><identifier>DOI: 10.12659/MSM.893403</identifier><identifier>PMID: 26110737</identifier><language>eng</language><publisher>United States: International Scientific Literature, Inc</publisher><subject>Aged ; alpha-2-HS-Glycoprotein - metabolism ; Clinical Research ; Diabetic Retinopathy - blood ; Diabetic Retinopathy - metabolism ; Female ; Humans ; Male ; Middle Aged ; Vitreous Body - metabolism</subject><ispartof>Medical science monitor, 2015-06, Vol.21, p.1839-1842</ispartof><rights>Med Sci Monit, 2015 2015</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c381t-ade16dc620060750d01233291f838e01129ade1329a8d75e1d93bdc7e38c0db3</citedby><cites>FETCH-LOGICAL-c381t-ade16dc620060750d01233291f838e01129ade1329a8d75e1d93bdc7e38c0db3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492483/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492483/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,886,27929,27930,53796,53798</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26110737$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhao, Chunming</creatorcontrib><creatorcontrib>Hou, Jiangping</creatorcontrib><creatorcontrib>Wang, Shengxi</creatorcontrib><creatorcontrib>Jiang, Rui</creatorcontrib><title>Relation of Serum and Vitreous Concentrations of Fetuin-A with Diabetic Retinopathy</title><title>Medical science monitor</title><addtitle>Med Sci Monit</addtitle><description>Fetuin-A, a liver-derived glycoprotein, is correlated with diabetes. The aim of the present investigation was to evaluate serum and vitreous concentrations of fetuin-A in patients with diabetic retinopathy (DR).
We randomly selected 224 diabetic patients and 68 control subjects for this study. RESULTS :There were markedly higher serum and vitreous fetuin-A concentrations in proliferative diabetic retinopathy (PDR) patients than in the other three groups. NPDR patients exhibited elevated vitreous fetuin-A concentrations compared with patients without DR. However, no significant differences in serum fetuin-A concentrations were observed between NPDR patients and patients without DR. In addition, there were significantly lower concentrations of serum and vitreous fetuin-A in control subjects compared with the other three groups.
The occurrence and severity of DR is correlated with serum and vitreous fetuin-A concentrations.</description><subject>Aged</subject><subject>alpha-2-HS-Glycoprotein - metabolism</subject><subject>Clinical Research</subject><subject>Diabetic Retinopathy - blood</subject><subject>Diabetic Retinopathy - metabolism</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Vitreous Body - metabolism</subject><issn>1643-3750</issn><issn>1234-1010</issn><issn>1643-3750</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkcFLwzAUxoMobk5P3iVHQTqTpk3TizCmU2FD2IbXkCapi7TNbFJl_73dOse8vDxefnzvSz4ArjEa4pDG6f1sMRuylESInIA-phEJSBKj06O-By6c-0QoZBTF56AXUoxRQpI-WMx1IbyxFbQ5XOi6KaGoFHw3vta2cXBsK6krX-8Yt4Um2jemCkbwx_gVfDQi095IOG9rZdfCrzaX4CwXhdNX-3MAlpOn5fglmL49v45H00AShn0glMZUSRoiRFFrUiEcEhKmOGeEaYRxmG6RdiKYSmKNVUoyJRNNmEQqIwPw0Mmum6zUqrNZ8HVtSlFvuBWG_7-pzIp_2G8eRWkYMdIK3O4FavvVaOd5aZzURSGq7ds5pimmCJMkadG7DpW1da7W-WENRnyXAm9T4F0KLX1z7OzA_n07-QWOr4Mt</recordid><startdate>20150625</startdate><enddate>20150625</enddate><creator>Zhao, Chunming</creator><creator>Hou, Jiangping</creator><creator>Wang, Shengxi</creator><creator>Jiang, Rui</creator><general>International Scientific Literature, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20150625</creationdate><title>Relation of Serum and Vitreous Concentrations of Fetuin-A with Diabetic Retinopathy</title><author>Zhao, Chunming ; Hou, Jiangping ; Wang, Shengxi ; Jiang, Rui</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c381t-ade16dc620060750d01233291f838e01129ade1329a8d75e1d93bdc7e38c0db3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Aged</topic><topic>alpha-2-HS-Glycoprotein - metabolism</topic><topic>Clinical Research</topic><topic>Diabetic Retinopathy - blood</topic><topic>Diabetic Retinopathy - metabolism</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Vitreous Body - metabolism</topic><toplevel>online_resources</toplevel><creatorcontrib>Zhao, Chunming</creatorcontrib><creatorcontrib>Hou, Jiangping</creatorcontrib><creatorcontrib>Wang, Shengxi</creatorcontrib><creatorcontrib>Jiang, Rui</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Medical science monitor</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhao, Chunming</au><au>Hou, Jiangping</au><au>Wang, Shengxi</au><au>Jiang, Rui</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Relation of Serum and Vitreous Concentrations of Fetuin-A with Diabetic Retinopathy</atitle><jtitle>Medical science monitor</jtitle><addtitle>Med Sci Monit</addtitle><date>2015-06-25</date><risdate>2015</risdate><volume>21</volume><spage>1839</spage><epage>1842</epage><pages>1839-1842</pages><issn>1643-3750</issn><issn>1234-1010</issn><eissn>1643-3750</eissn><abstract>Fetuin-A, a liver-derived glycoprotein, is correlated with diabetes. The aim of the present investigation was to evaluate serum and vitreous concentrations of fetuin-A in patients with diabetic retinopathy (DR).
We randomly selected 224 diabetic patients and 68 control subjects for this study. RESULTS :There were markedly higher serum and vitreous fetuin-A concentrations in proliferative diabetic retinopathy (PDR) patients than in the other three groups. NPDR patients exhibited elevated vitreous fetuin-A concentrations compared with patients without DR. However, no significant differences in serum fetuin-A concentrations were observed between NPDR patients and patients without DR. In addition, there were significantly lower concentrations of serum and vitreous fetuin-A in control subjects compared with the other three groups.
The occurrence and severity of DR is correlated with serum and vitreous fetuin-A concentrations.</abstract><cop>United States</cop><pub>International Scientific Literature, Inc</pub><pmid>26110737</pmid><doi>10.12659/MSM.893403</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
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| ispartof | Medical science monitor, 2015-06, Vol.21, p.1839-1842 |
| issn | 1643-3750 1234-1010 1643-3750 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; PubMed Central |
| subjects | Aged alpha-2-HS-Glycoprotein - metabolism Clinical Research Diabetic Retinopathy - blood Diabetic Retinopathy - metabolism Female Humans Male Middle Aged Vitreous Body - metabolism |
| title | Relation of Serum and Vitreous Concentrations of Fetuin-A with Diabetic Retinopathy |
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