Genome-wide copy-number variation study of psychosis in Alzheimer’s disease

About 40–60% of patients with late-onset Alzheimer’s disease (AD) develop psychosis, which represents a distinct phenotype of more severe cognitive and functional deficits. The estimated heritability of AD+P is ~61%, which makes it a good target for genetic mapping. We performed a genome-wide copy-n...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Translational psychiatry 2015-06, Vol.5 (6), p.e574-e574
Hauptverfasser:	Zheng, X, Demirci, F Y, Barmada, M M, Richardson, G A, Lopez, O L, Sweet, R A, Kamboh, M I, Feingold, E
Format:	Artikel
Sprache:	eng
Schlagworte:	45/43 45/47 Aged Aged, 80 and over Alzheimer Disease - genetics Alzheimer Disease - psychology Behavioral Sciences Biological Psychology Case-Control Studies Cell Cycle Proteins - genetics Cytoskeletal Proteins - genetics DNA Copy Number Variations Female Genetic Predisposition to Disease Genome-Wide Association Study Histone Chaperones - genetics Humans Intercellular Signaling Peptides and Proteins - genetics Jagged-2 Protein Male Medicine Medicine & Public Health Membrane Proteins - genetics Multivariate Analysis Neurosciences Nuclear Proteins - genetics Odds Ratio Original original-article Pharmacotherapy Phenotype Polymorphism, Single Nucleotide Psychiatry Psychosis Psychotic Disorders - genetics Psychotic Disorders - psychology Regression Analysis Severity of Illness Index Transcription Factors - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!