Therapeutic Strategies in Fragile X Syndrome: From Bench to Bedside and Back

Fragile X syndrome (FXS), an inherited intellectual disability often associated with autism, is caused by the loss of expression of the fragile X mental retardation protein. Tremendous progress in basic, preclinical, and translational clinical research has elucidated a variety of molecular-, cellula...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neurotherapeutics 2015-07, Vol.12 (3), p.584-608
Hauptverfasser:	Gross, Christina, Hoffmann, Anne, Bassell, Gary J., Berry-Kravis, Elizabeth M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Ataxia Autism Autism Spectrum Disorder - complications Behavior Biomarkers - metabolism Biomedical and Life Sciences Biomedicine Brain - metabolism Clinical trials Clinical Trials as Topic Cognitive ability Consortia Disease Models, Animal Female Fragile X Mental Retardation Protein - genetics Fragile X Mental Retardation Protein - metabolism Fragile X Syndrome - complications Fragile X Syndrome - genetics Fragile X Syndrome - therapy Humans Hyperactivity Impulsivity Intellectual disabilities Male Mice Mice, Knockout Mutation Neurobiology Neurology Neurons - metabolism Neurosciences Neurosurgery Ovaries Pediatrics Phenotype Proteins Review Standard scores Toxicity Translational Research, Biomedical
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!