Noncoding RNAs and enhancers: complications of a long-distance relationship

Spatial and temporal regulation of gene expression is achieved through instructions provided by the distal transcriptional regulatory elements known as enhancers. How enhancers transmit such information to their targets has been the subject of intense investigation. Recent advances in high throughpu...

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Veröffentlicht in:	Trends in genetics 2011-10, Vol.27 (10), p.433-439
Hauptverfasser:	Ørom, Ulf Andersson, Shiekhattar, Ramin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Enhancer Elements, Genetic Fundamental and applied biological sciences. Psychology Gene Expression Regulation Genetics of eukaryotes. Biological and molecular evolution Genome, Human Genomics - methods Humans Mammals Medical Education Mice Molecular and cellular biology RNA Polymerase II - genetics RNA Polymerase II - metabolism RNA, Untranslated - genetics RNA, Untranslated - metabolism Transcription, Genetic
Online-Zugang:	Volltext
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