Metallothionein-I/II Promotes Axonal Regeneration in the Central Nervous System

The adult CNS does not spontaneously regenerate after injury, due in large part to myelin-associated inhibitors such as myelin-associated glycoprotein (MAG), Nogo-A, and oligodendrocyte-myelin glycoprotein. All three inhibitors can interact with either the Nogo receptor complex or paired immunoglobu...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of biological chemistry 2015-06, Vol.290 (26), p.16343-16356
Hauptverfasser:	Siddiq, Mustafa M., Hannila, Sari S., Carmel, Jason B., Bryson, John B., Hou, Jianwei, Nikulina, Elena, Willis, Matthew R., Mellado, Wilfredo, Richman, Erica L., Hilaire, Melissa, Hart, Ronald P., Filbin, Marie T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals axonal regeneration Axons - metabolism central nervous system (CNS) Central Nervous System - injuries Central Nervous System - metabolism Central Nervous System - physiopathology cyclic AMP (cAMP) Female Male metallothionein Metallothionein - genetics Metallothionein - metabolism Mice, Knockout myelin Myelin Sheath - metabolism Myelin-Associated Glycoprotein - metabolism Nerve Regeneration neurite outgrowth Neurobiology Rats Rats, Long-Evans regeneration
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!