Enhanced GABAA-Mediated Tonic Inhibition in Auditory Thalamus of Rats with Behavioral Evidence of Tinnitus

Accumulating evidence suggests a role for inhibitory neurotransmitter dysfunction in the pathology of tinnitus. Opposing hypotheses proposed either a pathologic decrease or increase of GABAergic inhibition in medial geniculate body (MGB). In thalamus, GABA mediates fast synaptic inhibition via synap...

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Veröffentlicht in:	The Journal of neuroscience 2015-06, Vol.35 (25), p.9369-9380
Hauptverfasser:	Sametsky, Evgeny A, Turner, Jeremy G, Larsen, Deb, Ling, Lynne, Caspary, Donald M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Disease Models, Animal Geniculate Bodies - metabolism Geniculate Bodies - physiopathology In Situ Hybridization Male Neural Inhibition - physiology Patch-Clamp Techniques Rats Rats, Long-Evans Receptors, GABA-A - metabolism Synaptic Transmission - physiology Tinnitus - metabolism Tinnitus - physiopathology
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