Conversion to lacosamide monotherapy in the treatment of focal epilepsy: Results from a historical‐controlled, multicenter, double‐blind study

Summary Objective To evaluate the efficacy and safety of conversion to lacosamide 400 mg/day monotherapy in adults with focal epilepsy. Methods This historical‐controlled, double‐blind study (NCT00520741) enrolled patients aged 16–70 years on stable doses of 1–2 antiepileptic drugs (AEDs) and experi...

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Veröffentlicht in:	Epilepsia (Copenhagen) 2014-07, Vol.55 (7), p.1088-1098
Hauptverfasser:	Wechsler, Robert T., Li, George, French, Jacqueline, O'Brien, Terence J., D'Cruz, O'Neill, Williams, Paulette, Goodson, Robin, Brock, Melissa
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetamides - administration & dosage Acetamides - adverse effects Acetamides - standards Adolescent Adult Aged Anticonvulsants - administration & dosage Anticonvulsants - adverse effects Anticonvulsants - standards Confidence intervals Dose-Response Relationship, Drug Double-Blind Method Drug Administration Schedule Drug therapy Epilepsies, Partial - diagnosis Epilepsies, Partial - drug therapy Epilepsies, Partial - physiopathology Epilepsy Female Focal epilepsy Full-Length Original Research Headache - chemically induced Headache - diagnosis Historical control Humans Lacosamide Male Medical research Middle Aged Monotherapy Nausea - chemically induced Nausea - diagnosis Partial‐onset seizures Prospective Studies Treatment Outcome Young Adult
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