Human Endogenous Retrovirus Type K (HERV-K) Particles Package and Transmit HERV-K-Related Sequences

Human endogenous retroviruses (HERV) make up 8% of the human genome. While the youngest of these retroviruses, HERV-K(HML-2), termed HK2, is able to code for all viral proteins and produce virus-like particles, it is not known if these virus particles package and transmit HK2-related sequences. Here...

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Veröffentlicht in:	Journal of virology 2015-07, Vol.89 (14), p.7187-7201
Hauptverfasser:	Contreras-Galindo, Rafael, Kaplan, Mark H, Dube, Derek, Gonzalez-Hernandez, Marta J, Chan, Susana, Meng, Fan, Dai, Manhong, Omenn, Gilbert S, Gitlin, Scott D, Markovitz, David M
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line DNA, Viral - genetics DNA, Viral - metabolism Endogenous Retroviruses - genetics Endogenous Retroviruses - physiology Gene Transfer, Horizontal Genes, Reporter Genome and Regulation of Viral Gene Expression Human endogenous retrovirus Human immunodeficiency virus 1 Humans Reverse Transcription Transcription, Genetic Transduction, Genetic Virus Assembly
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