Homeostasis of redox status derived from glucose metabolic pathway could be the key to understanding the Warburg effect

Glucose metabolism in mitochondria through oxidative phosphorylation (OXPHOS) for generation of adenosine triphosphate (ATP) is vital for cell function. However, reactive oxygen species (ROS), a by-product from OXPHOS, is a major source of endogenously produced toxic stressors on the genome. In fact...

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Veröffentlicht in:American journal of cancer research 2015-01, Vol.5 (4), p.1265-1280
Hauptverfasser: Zhang, Shiwu, Yang, Chuanwei, Yang, Zhenduo, Zhang, Dan, Ma, Xiaoping, Mills, Gordon, Liu, Zesheng
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Sprache:eng
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