Adaptor protein CRK induces epithelial–mesenchymal transition and metastasis of bladder cancer cells through HGF/c‐Met feedback loop

We have previously reported that an adaptor protein CRK, including CRK‐I and CRK‐II, plays essential roles in the malignant potential of various aggressive human cancers, suggesting the validity of targeting CRK in molecular targeted therapy of a wide range of cancers. Nevertheless, the role of CRK...

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Veröffentlicht in:Cancer science 2015-06, Vol.106 (6), p.709-717
Hauptverfasser: Matsumoto, Ryuji, Tsuda, Masumi, Wang, Lei, Maishi, Nako, Abe, Takashige, Kimura, Taichi, Tanino, Mishie, Nishihara, Hiroshi, Hida, Kyoko, Ohba, Yusuke, Shinohara, Nobuo, Nonomura, Katsuya, Tanaka, Shinya
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Sprache:eng
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