trans-Hydrogenation: Application to a Concise and Scalable Synthesis of Brefeldin A

The important biochemical probe molecule brefeldin A (1) has served as an inspirational target in the past, but none of the many routes has actually delivered more than just a few milligrams of product, where documented. The approach described herein is clearly more efficient; it hinges upon the fir...

Ausführliche Beschreibung