Pathways Mediating Activity-Induced Enhancement of Recovery From Peripheral Nerve Injury
This article outlines the novel hypothesis that exercise promotes axon regeneration after peripheral nerve injury through neuronal brain-derived neurotrophic factor (BDNF), and there are three required means of promoting BDNF expression: 1) increased signaling through androgen receptors, 2) increase...
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| Veröffentlicht in: | Exercise and sport sciences reviews 2015-07, Vol.43 (3), p.163-171 |
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| container_title | Exercise and sport sciences reviews |
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| creator | Sabatier, Manning J English, Arthur W |
| description | This article outlines the novel hypothesis that exercise promotes axon regeneration after peripheral nerve injury through neuronal brain-derived neurotrophic factor (BDNF), and there are three required means of promoting BDNF expression: 1) increased signaling through androgen receptors, 2) increased cAMP-responsive element-binding protein expression, and 3) increased expression of the transcription factor SRY-box containing gene 11. |
| doi_str_mv | 10.1249/JES.0000000000000047 |
| format | Article |
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| ispartof | Exercise and sport sciences reviews, 2015-07, Vol.43 (3), p.163-171 |
| issn | 0091-6331 1538-3008 |
| language | eng |
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| source | MEDLINE; Journals@Ovid LWW Legacy Archive; EZB-FREE-00999 freely available EZB journals |
| subjects | Animals Axons - physiology Brain-Derived Neurotrophic Factor - physiology Cyclic AMP Response Element-Binding Protein - metabolism Humans Nerve Regeneration - physiology Peripheral Nerve Injuries - physiopathology Receptors, Androgen - metabolism Signal Transduction SOXC Transcription Factors - metabolism |
| title | Pathways Mediating Activity-Induced Enhancement of Recovery From Peripheral Nerve Injury |
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