Structural variation discovery in the cancer genome using next generation sequencing: computational solutions and perspectives

Somatic Structural Variations (SVs) are a complex collection of chromosomal mutations that could directly contribute to carcinogenesis. Next Generation Sequencing (NGS) technology has emerged as the primary means of interrogating the SVs of the cancer genome in recent investigations. Sophisticated c...

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Veröffentlicht in:	Oncotarget 2015-03, Vol.6 (8), p.5477-5489
Hauptverfasser:	Liu, Biao, Conroy, Jeffrey M, Morrison, Carl D, Odunsi, Adekunle O, Qin, Maochun, Wei, Lei, Trump, Donald L, Johnson, Candace S, Liu, Song, Wang, Jianmin
Format:	Artikel
Sprache:	eng
Schlagworte:	Genomic Structural Variation Genomics - methods Humans Neoplasms - genetics Review Sequence Analysis, DNA - methods
Online-Zugang:	Volltext
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