Olfactory ensheathing cell tumor: A case report and review of the literature
Olfactory ensheathing cell tumors (OECTs) are rare malignancies that occur in the anterior fossa. Little is known with regard to their clinical, radiological and immunohistochemical characteristics. The current study reports the case of a 20-year-old male with an OECT, who presented with a severe he...
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| Veröffentlicht in: | Oncology letters 2015-05, Vol.9 (5), p.2078-2084 |
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| creator | MU, QINGCHUN GAO, HAIJUN LIU, PENGFEI HU, XITONG ZHENG, XU LI, PEIWEN LEI, TING SUN, YUXUE ZHAO, GANG HUANG, HAIYAN HONG, XINYU |
| description | Olfactory ensheathing cell tumors (OECTs) are rare malignancies that occur in the anterior fossa. Little is known with regard to their clinical, radiological and immunohistochemical characteristics. The current study reports the case of a 20-year-old male with an OECT, who presented with a severe headache and a generalized convulsion. Cranial magnetic resonance imaging revealed heterogeneous enhancement of the tumor in the left anterior fossa. Complete removal of the tumor via a left frontal craniotomy was conducted, which relieved the patient's headache; however, this resulted in left-sided anosmia that remained during the two-month follow-up. The tumor was immunopositive for vimentin and S-100, and immunonegative for epithelial membrane antigen and Leu-7. The clinical data, imaging features, intraoperative findings and immunohistochemical characteristics of an additional seven cases reported in the literature are also reviewed and analyzed, providing important clinical information for the pre-operative diagnosis and intraoperative removal of OECTs. |
| doi_str_mv | 10.3892/ol.2015.3042 |
| format | Article |
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Spandidos</publisher><subject>Care and treatment ; Case studies ; Craniotomy ; Diagnosis ; Health aspects ; immunohistochemistry ; Magnetic resonance imaging ; olfactory ensheathing cell tumor ; olfactory groove schwannoma ; Tumors</subject><ispartof>Oncology letters, 2015-05, Vol.9 (5), p.2078-2084</ispartof><rights>Copyright © 2015, Spandidos Publications</rights><rights>COPYRIGHT 2015 Spandidos Publications</rights><rights>Copyright © 2015, Spandidos Publications 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c511t-a46826f7ec07b8c88053333395e493ffd24e5f9f11a5c0c8f139f1146de15a3c3</citedby><cites>FETCH-LOGICAL-c511t-a46826f7ec07b8c88053333395e493ffd24e5f9f11a5c0c8f139f1146de15a3c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467262/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467262/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,5555,27903,27904,53770,53772</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26137016$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>MU, QINGCHUN</creatorcontrib><creatorcontrib>GAO, HAIJUN</creatorcontrib><creatorcontrib>LIU, PENGFEI</creatorcontrib><creatorcontrib>HU, XITONG</creatorcontrib><creatorcontrib>ZHENG, XU</creatorcontrib><creatorcontrib>LI, PEIWEN</creatorcontrib><creatorcontrib>LEI, TING</creatorcontrib><creatorcontrib>SUN, YUXUE</creatorcontrib><creatorcontrib>ZHAO, GANG</creatorcontrib><creatorcontrib>HUANG, HAIYAN</creatorcontrib><creatorcontrib>HONG, XINYU</creatorcontrib><title>Olfactory ensheathing cell tumor: A case report and review of the literature</title><title>Oncology letters</title><addtitle>Oncol Lett</addtitle><description>Olfactory ensheathing cell tumors (OECTs) are rare malignancies that occur in the anterior fossa. Little is known with regard to their clinical, radiological and immunohistochemical characteristics. The current study reports the case of a 20-year-old male with an OECT, who presented with a severe headache and a generalized convulsion. Cranial magnetic resonance imaging revealed heterogeneous enhancement of the tumor in the left anterior fossa. Complete removal of the tumor via a left frontal craniotomy was conducted, which relieved the patient's headache; however, this resulted in left-sided anosmia that remained during the two-month follow-up. The tumor was immunopositive for vimentin and S-100, and immunonegative for epithelial membrane antigen and Leu-7. The clinical data, imaging features, intraoperative findings and immunohistochemical characteristics of an additional seven cases reported in the literature are also reviewed and analyzed, providing important clinical information for the pre-operative diagnosis and intraoperative removal of OECTs.</description><subject>Care and treatment</subject><subject>Case studies</subject><subject>Craniotomy</subject><subject>Diagnosis</subject><subject>Health aspects</subject><subject>immunohistochemistry</subject><subject>Magnetic resonance imaging</subject><subject>olfactory ensheathing cell tumor</subject><subject>olfactory groove schwannoma</subject><subject>Tumors</subject><issn>1792-1074</issn><issn>1792-1082</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNptks9rHCEUx4fS0oQ0t56L0FJy6GzVcRwnh8IS0h-wsJf2LMZ57lgc3aqTkv--TjddslDfwad-3hffj6p6TfCqET39GNyKYtKuGszos-qcdD2tCRb0-dHv2Fl1mdJPXFbLiRD8ZXVGOWk6TPh5tdk6o3QO8QGBTyOoPFq_QxqcQ3meQrxGa6RVAhRhH2JGyg_FvbfwGwWD8gjI2QxR5TnCq-qFUS7B5eN-Uf34fPv95mu92X75drPe1LolJNeKcUG56UDj7k5oIXDbLKtvgfWNMQNl0JreEKJajbUwpFkOjA9AWtXo5qL6dNDdz3cTDBp8jsrJfbSTig8yKCtPX7wd5S7cS8Z4RzktAlePAjH8miFlOdm05Kw8hDlJUv5XMNbzgr49oDvlQFpvQlHUCy7XjJZaN5wv1Oo_VLEBJquDB2PL_UnA-ycBpe4ujym4Odvg0yn44QDqGFKKYI5pEiyXGZDByWUG5DIDBX_ztDRH-F_HC_DuAKR9aaUdQjoy202Ni_3V-QOpn7YV</recordid><startdate>20150501</startdate><enddate>20150501</enddate><creator>MU, QINGCHUN</creator><creator>GAO, HAIJUN</creator><creator>LIU, PENGFEI</creator><creator>HU, XITONG</creator><creator>ZHENG, XU</creator><creator>LI, PEIWEN</creator><creator>LEI, TING</creator><creator>SUN, YUXUE</creator><creator>ZHAO, GANG</creator><creator>HUANG, HAIYAN</creator><creator>HONG, XINYU</creator><general>D.A. 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| source | Spandidos Publications Journals; PubMed Central; EZB Electronic Journals Library |
| subjects | Care and treatment Case studies Craniotomy Diagnosis Health aspects immunohistochemistry Magnetic resonance imaging olfactory ensheathing cell tumor olfactory groove schwannoma Tumors |
| title | Olfactory ensheathing cell tumor: A case report and review of the literature |
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