Dexmedetomidine protects against acute kidney injury through downregulating inflammatory reactions in endotoxemia rats

Approximately 42% of patients with sepsis undergo acute kidney injury (AKI), which evidently influences patient survival. However, effective therapy strategies are lacking, thus, the present study investigated the protective effects of dexmedetomidine (DEX), a highly selective α-2 adrenoceptor agoni...

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Veröffentlicht in:	Biomedical reports 2015-05, Vol.3 (3), p.365-370
Hauptverfasser:	TAN, FANG, CHEN, YUJIE, YUAN, DONGDONG, GONG, CULIAN, LI, XIAOYUN, ZHOU, SHAOLI
Format:	Artikel
Sprache:	eng
Schlagworte:	acute kidney injury Dexmedetomidine Dosage and administration Drug therapy Kidney diseases kidney injury molecule α-2 adrenergic receptor
Online-Zugang:	Volltext
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