Antigen-specific H1N1 influenza antibody responses in acute respiratory tract infections and their relation to influenza infection and disease course

Highlights • Lower H1-influenza-specific antibodies were associated with influenza infection. • Higher antibodies in patients with longer duration and higher symptom scores. • In flu patients higher antibody titers were seen in admitted patients.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of clinical virology 2014-08, Vol.60 (4), p.367-373
Hauptverfasser:	Haran, John Patrick, Hoaglin, David C, Chen, Huaiqing, Boyer, Edward W, Lu, Shan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Allergy and Immunology Antibodies Antibodies, Neutralizing Antibodies, Viral - blood Antibody Formation Bacterial pneumonia Disease Progression Female H1N1 influenza Hemagglutination Inhibition Tests Hemagglutinins, Viral - immunology Humans Infectious Disease Influenza A Virus, H1N1 Subtype - immunology Influenza, Human - diagnosis Influenza, Human - immunology Influenza, Human - virology Male Respiratory Tract Infections - complications Respiratory Tract Infections - immunology Seasonal influenza
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Beschreibung
Zusammenfassung:	Highlights • Lower H1-influenza-specific antibodies were associated with influenza infection. • Higher antibodies in patients with longer duration and higher symptom scores. • In flu patients higher antibody titers were seen in admitted patients.
ISSN:	1386-6532 1873-5967
DOI:	10.1016/j.jcv.2014.04.017