Propolis: A Complex Natural Product with a Plethora of Biological Activities That Can Be Explored for Drug Development
The health industry has always used natural products as a rich, promising, and alternative source of drugs that are used in the health system. Propolis, a natural resinous product known for centuries, is a complex product obtained by honey bees from substances collected from parts of different plant...
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| Veröffentlicht in: | Evidence-based complementary and alternative medicine 2015-01, Vol.2015 (2015), p.1-29 |
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| creator | Silva-Carvalho, Ricardo Almeida-Aguiar, Cristina Baltazar, Fátima |
| description | The health industry has always used natural products as a rich, promising, and alternative source of drugs that are used in the health system. Propolis, a natural resinous product known for centuries, is a complex product obtained by honey bees from substances collected from parts of different plants, buds, and exudates in different geographic areas. Propolis has been attracting scientific attention since it has many biological and pharmacological properties, which are related to its chemical composition. Several in vitro and in vivo studies have been performed to characterize and understand the diverse bioactivities of propolis and its isolated compounds, as well as to evaluate and validate its potential. Yet, there is a lack of information concerning clinical effectiveness. The goal of this review is to discuss the potential of propolis for the development of new drugs by presenting published data concerning the chemical composition and the biological properties of this natural compound from different geographic origins. |
| doi_str_mv | 10.1155/2015/206439 |
| format | Article |
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Propolis, a natural resinous product known for centuries, is a complex product obtained by honey bees from substances collected from parts of different plants, buds, and exudates in different geographic areas. Propolis has been attracting scientific attention since it has many biological and pharmacological properties, which are related to its chemical composition. Several in vitro and in vivo studies have been performed to characterize and understand the diverse bioactivities of propolis and its isolated compounds, as well as to evaluate and validate its potential. Yet, there is a lack of information concerning clinical effectiveness. The goal of this review is to discuss the potential of propolis for the development of new drugs by presenting published data concerning the chemical composition and the biological properties of this natural compound from different geographic origins.</description><identifier>ISSN: 1741-427X</identifier><identifier>EISSN: 1741-4288</identifier><identifier>DOI: 10.1155/2015/206439</identifier><identifier>PMID: 26106433</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Publishing Corporation</publisher><subject>Apis mellifera ; Cell cycle ; Dehydrogenases ; Drug discovery ; Drugs ; Health sciences ; Honeybee ; Laboratories ; Medicine ; Natural products ; Properties ; Propolis ; R&D ; Research & development ; Review</subject><ispartof>Evidence-based complementary and alternative medicine, 2015-01, Vol.2015 (2015), p.1-29</ispartof><rights>Copyright © 2015 Ricardo Silva-Carvalho et al.</rights><rights>COPYRIGHT 2015 John Wiley & Sons, Inc.</rights><rights>Copyright © 2015 Ricardo Silva-Carvalho et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</rights><rights>Copyright © 2015 Ricardo Silva-Carvalho et al. 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c553t-b2cae93d3c72ecb69db64c803d1a79dbb7581744f3c9d06e03f222e4eacfdc2f3</citedby><cites>FETCH-LOGICAL-c553t-b2cae93d3c72ecb69db64c803d1a79dbb7581744f3c9d06e03f222e4eacfdc2f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461776/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461776/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26106433$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Bastos, Jairo Kennup</contributor><creatorcontrib>Silva-Carvalho, Ricardo</creatorcontrib><creatorcontrib>Almeida-Aguiar, Cristina</creatorcontrib><creatorcontrib>Baltazar, Fátima</creatorcontrib><title>Propolis: A Complex Natural Product with a Plethora of Biological Activities That Can Be Explored for Drug Development</title><title>Evidence-based complementary and alternative medicine</title><addtitle>Evid Based Complement Alternat Med</addtitle><description>The health industry has always used natural products as a rich, promising, and alternative source of drugs that are used in the health system. 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Propolis, a natural resinous product known for centuries, is a complex product obtained by honey bees from substances collected from parts of different plants, buds, and exudates in different geographic areas. Propolis has been attracting scientific attention since it has many biological and pharmacological properties, which are related to its chemical composition. Several in vitro and in vivo studies have been performed to characterize and understand the diverse bioactivities of propolis and its isolated compounds, as well as to evaluate and validate its potential. Yet, there is a lack of information concerning clinical effectiveness. 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| ispartof | Evidence-based complementary and alternative medicine, 2015-01, Vol.2015 (2015), p.1-29 |
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| source | PubMed Central Open Access; Wiley-Blackwell Open Access Titles; EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Apis mellifera Cell cycle Dehydrogenases Drug discovery Drugs Health sciences Honeybee Laboratories Medicine Natural products Properties Propolis R&D Research & development Review |
| title | Propolis: A Complex Natural Product with a Plethora of Biological Activities That Can Be Explored for Drug Development |
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