Synthesis, development, characterization and effectiveness of bovine pure platelet gel‐collagen‐polydioxanone bioactive graft on tendon healing

Bovine platelet gel (BPG) is an accessible and cost‐effective source of growth factors which may have a value in tendon regenerative medicine. We produced a collagen implant (CI) as a tendon proper, covered it with polydioxanone (PDS) sheath to simulate paratenon and finally embedded the BPG as an a...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2015-06, Vol.19 (6), p.1308-1332
Hauptverfasser:	Moshiri, Ali, Oryan, Ahmad, Meimandi‐Parizi, Abdolhamid
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorbable Implants Achilles Tendon - injuries Animals Atrophy bioactive graft Biocompatibility Biodegradability Biodegradation Blood Platelets - metabolism bovine platelet gel Cattle Cell differentiation Cell viability Collagen Collagen (type I) Collagen - metabolism Computer simulation Defects Differentiation (biology) Dry matter Fibrosis Gels - metabolism Grafting Grafts Growth factors healing Inflammation Male Microscopy, Electron, Scanning modelling Muscles Original Physical characteristics Plastic surgery Platelet-derived growth factor Platelet-Derived Growth Factor - metabolism Platelets Polydioxanone - metabolism Rabbits Reconstructive surgery Regenerative medicine remodelling Scanning electron microscopy Studies Surgery Tendon Injuries - blood Tendon Injuries - surgery Tendons Tissue engineering Tissue Engineering - methods Tissue Scaffolds Tissue Transplantation - methods Transplantation, Heterologous Transplants & implants Viability Water treatment Water uptake Wound Healing
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