Dysrhythmia in the suprachiasmatic nucleus inhibits memory processing

Chronic circadian dysfunction impairs declarative memory in humans but has little effect in common rodent models of arrhythmia caused by clock gene knockouts or surgical ablation of the suprachiasmatic nucleus (SCN). An important problem overlooked in these translational models is that human dysrhyt...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Science (American Association for the Advancement of Science) 2014-11, Vol.346 (6211), p.854-857
Hauptverfasser:	Fernandez, Fabian, Lu, Derek, Ha, Phong, Costacurta, Patricia, Chavez, Renee, Heller, H. Craig, Ruby, Norman F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Ablation Animal memory Animal models Animals arrhythmia Circadian rhythm Cognition Dysrhythmias Electric circuits Flagella genes Hamsters humans Impairment Information processing Lesions Mazes Memory Memory disorders Neurobiology Phodopus Phodopus sungorus Recognition Rhythm Rodents Suprachiasmatic nucleus surgical ablation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!