Imprinted expression in cystic embryoid bodies shows an embryonic and not an extra-embryonic pattern

A large subset of mammalian imprinted genes show extra-embryonic lineage (EXEL) specific imprinted expression that is restricted to placental trophectoderm lineages and to visceral yolk sac endoderm (ysE). Isolated ysE provides a homogenous in vivo model of a mid-gestation extra-embryonic tissue to...

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Veröffentlicht in:	Developmental biology 2015-06, Vol.402 (2), p.291-305
Hauptverfasser:	Kulinski, Tomasz M., Casari, M. Rita T., Guenzl, Philipp M., Wenzel, Daniel, Andergassen, Daniel, Hladik, Anastasiya, Datlinger, Paul, Farlik, Matthias, Theussl, H. -Christian, Penninger, Josef M., Knapp, Sylvia, Bock, Christoph, Barlow, Denise P., Hudson, Quanah J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Cell Differentiation - physiology Chromatin Immunoprecipitation Computational Biology cost effectiveness Cystic embryoid bodies (EBs) DNA Methylation Embryoid Bodies - metabolism Endoderm - metabolism epigenetics Gene Expression Profiling Gene Expression Regulation, Developmental - genetics gene silencing genes genome-wide association study Genomes and Developmental Control Genomic imprinting Genomic Imprinting - genetics Histological Techniques In Situ Hybridization liver mammals Mice Models, Biological Molecular Sequence Data placenta sequence analysis Sequence Analysis, RNA transcriptome transcriptomics Visceral endoderm (VE) Visceral yolk sac (VYS) Visceral yolk sac Endoderm (ysE) yolk sac Yolk Sac - cytology Yolk Sac - metabolism
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