Sialidase NEU4 is involved in glioblastoma stem cell survival

The human sialidase, NEU4, has emerged as a possible regulator of neuronal differentiation and its overexpression has been demonstrated to promote the acquisition of a stem cell-like phenotype in neuroblastoma cells. In this paper, we demonstrated that glioblastoma stem cells (GSCs) isolated from gl...

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Veröffentlicht in:	Cell death & disease 2014-08, Vol.5 (8), p.e1381-e1381
Hauptverfasser:	Silvestri, I, Testa, F, Zappasodi, R, Cairo, C W, Zhang, Y, Lupo, B, Galli, R, Di Nicola, M, Venerando, B, Tringali, C
Format:	Artikel
Sprache:	eng
Schlagworte:	13/100 13/106 38 38/1 38/77 38/89 631/67/1922 631/67/71 631/80/86 96 96/2 96/34 96/44 96/95 AC133 Antigen Antibodies Antigens, CD - genetics Antigens, CD - metabolism Biochemistry Biomedical and Life Sciences Cell Biology Cell Culture Cell Line, Tumor Cell Survival Gangliosides - metabolism Gene Silencing Glioblastoma - metabolism Glioblastoma - pathology Glycogen Synthase Kinase 3 - metabolism Glycogen Synthase Kinase 3 beta Glycoproteins - genetics Glycoproteins - metabolism Hedgehog Proteins - genetics Hedgehog Proteins - metabolism Homeodomain Proteins - genetics Homeodomain Proteins - metabolism Humans Immunology Life Sciences MicroRNAs - genetics MicroRNAs - metabolism Nanog Homeobox Protein Neoplastic Stem Cells - cytology Neoplastic Stem Cells - metabolism Neuraminidase - antagonists & inhibitors Neuraminidase - genetics Neuraminidase - metabolism Octamer Transcription Factor-3 - genetics Octamer Transcription Factor-3 - metabolism Original original-article Peptides - genetics Peptides - metabolism SOXB1 Transcription Factors - genetics SOXB1 Transcription Factors - metabolism Wnt Signaling Pathway
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