Myosin‑II heavy chain and formin mediate the targeting of myosin essential light chain to the division site before and during cytokinesis

MLC1 is a haploinsufficient gene encoding the essential light chain for Myo1, the sole myosin‑II heavy chain in the budding yeast Saccharomyces cerevisiae. Mlc1 defines an essential hub that coordinates actomyosin ring function, membrane trafficking, and septum formation during cytokinesis by bindin...

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Veröffentlicht in:	Molecular biology of the cell 2015-04, Vol.26 (7), p.1211-1224
Hauptverfasser:	Feng, Zhonghui, Okada, Satoshi, Cai, Guoping, Zhou, Bing, Bi, Erfei
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Cytoskeleton - metabolism Cell Division - physiology Cytokinesis - physiology Cytoskeletal Proteins - metabolism Microfilament Proteins - metabolism Myosin Heavy Chains - metabolism Myosin Light Chains - metabolism Protein Transport Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae - physiology Saccharomyces cerevisiae Proteins - metabolism Septins - metabolism
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