Preparation of Porous Chitosan-Siloxane Hybrids Coated with Hydroxyapatite Particles

Preparation of Porous Chitosan-Siloxane Hybrids Coated with Hydroxyapatite Particles

This paper describes the apatite deposition of chitosan-silicate porous hybrids derived from chitosan and γ-glycidoxypropyltrimethoxysilane (GPTMS) in alkaline phosphate solution. The preparation of porous hybrids with needle-like apatite on their surfaces is described. Following apatite deposition...

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Veröffentlicht in:BioMed research international 2015-01, Vol.2015 (2015), p.1-6
Hauptverfasser: Osaka, Akiyoshi, Hayakawa, Satoshi, Okamoto, Kohei, Shirosaki, Yuki, Asano, Takuji
Format: Artikel
Sprache:eng
Schlagworte:
Apatite
Atoms & subatomic particles
Brain research
Chitin
Chitosan - chemical synthesis
Chitosan - chemistry
Coating
Craniotomy
Cutting tools
Degradation
Deposition
Durapatite - chemical synthesis
Durapatite - chemistry
Equipment and supplies
Humans
Hydroxyapatite
Medical supplies
Molecular weight
Phosphates
Porosity
Product development
Silicates - chemistry
Siloxanes
Siloxanes - chemical synthesis
Siloxanes - chemistry
Studies
Tissue Scaffolds
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Zusammenfassung:This paper describes the apatite deposition of chitosan-silicate porous hybrids derived from chitosan and γ-glycidoxypropyltrimethoxysilane (GPTMS) in alkaline phosphate solution. The preparation of porous hybrids with needle-like apatite on their surfaces is described. Following apatite deposition the porous hybrids maintained high porosity. The enzymatic degradation rate was low even after 6 months and the porous hybrids were very flexible and cut easily using surgical scissors.
ISSN:2314-6133
2314-6141
DOI:10.1155/2015/392940