Molecular architecture and function of the hemidesmosome

Hemidesmosomes are multiprotein complexes that facilitate the stable adhesion of basal epithelial cells to the underlying basement membrane. The mechanical stability of hemidesmosomes relies on multiple interactions of a few protein components that form a membrane-embedded tightly-ordered complex. T...

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Veröffentlicht in:	Cell and tissue research 2015-06, Vol.360 (3), p.529-544
Hauptverfasser:	Walko, Gernot, Castañón, Maria J., Wiche, Gerhard
Format:	Artikel
Sprache:	eng
Schlagworte:	adhesion Animals antigens basement membrane Basement Membrane - metabolism Biomedical and Life Sciences Biomedicine carcinoma Cells Collagen cytoskeleton epithelial cells extracellular matrix Hemidesmosomes - metabolism Human Genetics Humans Integrins Intermediate Filaments - metabolism Keratin keratinocytes Models, Biological Molecular Medicine multiprotein complexes Protein Binding Protein Processing, Post-Translational Proteins Proteomics Review tissue repair transcription (genetics)
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