QRFP-26 enhances insulin's effects on glucose uptake in rat skeletal muscle cells

•Prepro-QRFP mRNA and GRP103a mRNA are expressed in differentiated L6 myotubes.•QRFP-26 enhanced insulin-stimulated glycogen synthesis and 2-DG uptake.•QRFP-43 did not affect insulin's action on glycogen synthesis and 2-DG uptake. QRFP is expressed in central and peripheral regions important fo...

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Veröffentlicht in:	Peptides (New York, N.Y. : 1980) N.Y. : 1980), 2015-07, Vol.69, p.77-79
Hauptverfasser:	Allerton, Timothy D., Primeaux, Stefany D.
Format:	Artikel
Sprache:	eng
Schlagworte:	2-deoxyglucose adipocytes Animals cell culture Eating - drug effects Eating - genetics fatty acids Female females glucose Glucose - metabolism Glucose uptake glycogen Glycogen - biosynthesis GPR103a high fat diet Humans insulin Insulin - administration & dosage Insulin - metabolism islets of Langerhans L6 cells Male males messenger RNA metabolism Muscle, Skeletal - drug effects Muscle, Skeletal - metabolism Muscle, Skeletal - pathology myotubes nutrient intake Peptides - administration & dosage Peptides - metabolism QRFP-26 QRFP-43 Rats receptors Receptors, G-Protein-Coupled - biosynthesis Receptors, G-Protein-Coupled - metabolism RNA, Messenger - biosynthesis skeletal muscle
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