Mechanistic Insights into the Anchorage of the Contractile Ring by Anillin and Mid1

Anillins and Mid1 are scaffold proteins that play key roles in anchorage of the contractile ring at the cell equator during cytokinesis in animals and fungi, respectively. Here, we report crystal structures and functional analysis of human anillin and S. pombe Mid1. The combined data show anillin co...

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Veröffentlicht in:	Developmental cell 2015-05, Vol.33 (4), p.413-426
Hauptverfasser:	Sun, Lingfei, Guan, Ruifang, Lee, I-Ju, Liu, Yajun, Chen, Mengran, Wang, Jiawei, Wu, Jian-Qiu, Chen, Zhucheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Cytoskeleton - metabolism Amino Acid Sequence Cell Membrane - metabolism Crystallography, X-Ray Cytokinesis - physiology Humans Microfilament Proteins - chemistry Microfilament Proteins - metabolism Molecular Sequence Data Phospholipids - metabolism Protein Structure, Tertiary rhoA GTP-Binding Protein - chemistry rhoA GTP-Binding Protein - metabolism Schizosaccharomyces pombe Proteins - chemistry Schizosaccharomyces pombe Proteins - metabolism
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