Phase I Trial of Repeated Intrathecal Autologous Bone Marrow‐Derived Mesenchymal Stromal Cells in Amyotrophic Lateral Sclerosis

The aim of this open‐label phase I clinical trial is to evaluate the safety of two repeated intrathecal injections of autologous bone marrow (BM)‐derived mesenchymal stromal cells (MSCs) in amyotrophic lateral sclerosis patients. With the exception of 1 patient who died before the bone marrow extrac...

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Veröffentlicht in:	Stem cells translational medicine 2015-06, Vol.4 (6), p.590-597
Hauptverfasser:	Oh, Ki-Wook, Moon, Chanil, Kim, Hyun Young, Oh, Sung-il, Park, Jinseok, Lee, Jun Ho, Chang, In Young, Kim, Kyung Suk, Kim, Seung Hyun
Format:	Artikel
Sprache:	eng
Schlagworte:	Administrative support Adult Aged Amyotrophic lateral sclerosis Amyotrophic Lateral Sclerosis - physiopathology Amyotrophic Lateral Sclerosis - therapy Autografts Bone marrow Bone Marrow Cells Cell-Based Drug Development, Screening, and Toxicology Clinical trials Data analysis Drug dosages FDA approval Female Follow-Up Studies Humans Intrathecal Male Mesenchymal Stem Cell Transplantation Mesenchymal stem cells Mesenchymal Stromal Cells Mesenchyme Middle Aged Patients Spinal cord Stem cells Stromal cells Studies
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