Characterization of the target of ivermectin, the glutamate-gated chloride channel, from Anopheles gambiae

The use of insecticide-treated nets and indoor residual insecticides targeting adult mosquito vectors is a key element in malaria control programs. However, mosquito resistance to the insecticides used in these applications threatens malaria control efforts. Recently, the mass drug administration of...

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Veröffentlicht in:	Journal of experimental biology 2015-05, Vol.218 (Pt 10), p.1478-1486
Hauptverfasser:	Meyers, Jacob I, Gray, Meg, Kuklinski, Wojtek, Johnson, Lucas B, Snow, Christopher D, Black, 4th, William C, Partin, Kathryn M, Foy, Brian D
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Alternative Splicing Animals Anopheles - drug effects Anopheles - metabolism Chloride Channels - antagonists & inhibitors Chloride Channels - genetics Chloride Channels - metabolism Female Glutamic Acid - pharmacology Insect Vectors Insecticides - pharmacology Ivermectin - pharmacology Male Oocytes - physiology Xenopus laevis
Online-Zugang:	Volltext
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