Whole-Exome Sequencing Studies of Nonfunctioning Pituitary Adenomas

Context: The tumorigenic role of genetic abnormalities in sporadic pituitary nonfunctioning adenomas (NFAs), which usually originate from gonadotroph cells, is unknown. Objective: The objective of the study was to identify somatic genetic abnormalities in sporadic pituitary NFAs. Design: Whole-exome...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2013-04, Vol.98 (4), p.E796-E800
Hauptverfasser:	Newey, Paul J, Nesbit, M. Andrew, Rimmer, Andrew J, Head, Rosie A, Gorvin, Caroline M, Attar, Moustafa, Gregory, Lorna, Wass, John A. H, Buck, David, Karavitaki, Niki, Grossman, Ashley B, McVean, Gilean, Ansorge, Olaf, Thakker, Rajesh V
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoma - epidemiology Adenoma - genetics Adenoma - physiopathology Adult Aged Aged, 80 and over DNA Mutational Analysis Exome - genetics Female Gene Expression Regulation, Neoplastic Genetic Association Studies Humans JCEM Online: Advances in Genetics Male Microarray Analysis Middle Aged Mutation - physiology Pituitary Neoplasms - epidemiology Pituitary Neoplasms - genetics Pituitary Neoplasms - physiopathology Sequence Analysis, DNA - methods Transcriptome
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