A coupled model of neovessel growth and matrix mechanics describes and predicts angiogenesis in vitro

During angiogenesis, sprouting microvessels interact with the extracellular matrix (ECM) by degrading and reorganizing the matrix, applying traction forces, and producing deformation. Morphometric features of the resulting microvascular network are affected by the interaction between the matrix and...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biomechanics and modeling in mechanobiology 2015-08, Vol.14 (4), p.767-782
Hauptverfasser:	Edgar, Lowell T., Maas, Steve A., Guilkey, James E., Weiss, Jeffrey A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alignment Angiogenesis Animals Biodegradation Biological and Medical Physics Biomechanical Phenomena Biomedical Engineering and Bioengineering Biophysics Blood Vessels - growth & development Boundary conditions Computer Simulation Deformation Electrochemical machining Engineering Extracellular Matrix - physiology Finite Element Analysis Finite element method In vitro testing Joining Male Mathematical models Matrix Mechanical properties Microvessels - physiology Models, Biological Neovascularization, Physiologic Nonlinear Dynamics Original Paper Rats, Sprague-Dawley Space life sciences Stress, Mechanical Theoretical and Applied Mechanics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!