Utility of the low-accelerating-dose regimen in 182 liver recipients with recurrent hepatitis C virus

To describe our experience using a low-accelerating-dose regimen (LADR) with pegylated interferon alpha-2a and ribavirin in treatment of hepatitis C virus (HCV) recurrence. From 2003, a protocolized LADR strategy was employed to treat liver transplant (LT) recipients with recurrent HCV at our instit...

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Veröffentlicht in:	World journal of gastroenterology : WJG 2015-05, Vol.21 (20), p.6236-6245
Hauptverfasser:	Lim, Kieron B L, Sima, Hamid R, Fiel, M Isabel, Khaitova, Viktoriya, Doucette, John T, Chernyiak, Maria, Ahmad, Jawad, Bach, Nancy, Chang, Charissa, Grewal, Priya, Kim-Schluger, Leona, Liu, Lawrence, Odin, Joseph, Perumalswami, Ponni, Florman, Sander S, Schiano, Thomas D
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral Agents - administration & dosage Antiviral Agents - adverse effects Biopsy Disease Progression Drug Therapy, Combination End Stage Liver Disease - diagnosis End Stage Liver Disease - surgery End Stage Liver Disease - virology Female Genotype Graft Survival Hepacivirus - drug effects Hepacivirus - genetics Hepacivirus - growth & development Hepatitis C - complications Hepatitis C - diagnosis Hepatitis C - drug therapy Hepatitis C - genetics Hepatitis C - mortality Humans Interferon-alpha - administration & dosage Interferon-alpha - adverse effects Interferons Interleukins - genetics Liver Transplantation - adverse effects Liver Transplantation - mortality Male Middle Aged New York City Polyethylene Glycols - administration & dosage Polyethylene Glycols - adverse effects Proportional Hazards Models Recombinant Proteins - administration & dosage Recombinant Proteins - adverse effects Recurrence Retrospective Studies Retrospective Study Ribavirin - administration & dosage Ribavirin - adverse effects Risk Factors Time Factors Treatment Outcome Viral Load Virus Activation - drug effects
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