TIMMA-R: an R package for predicting synergistic multi-targeted drug combinations in cancer cell lines or patient-derived samples

Network pharmacology-based prediction of multi-targeted drug combinations is becoming a promising strategy to improve anticancer efficacy and safety. We developed a logic-based network algorithm, called Target Inhibition Interaction using Maximization and Minimization Averaging (TIMMA), which predic...

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Veröffentlicht in:Bioinformatics 2015-06, Vol.31 (11), p.1866-1868
Hauptverfasser: He, Liye, Wennerberg, Krister, Aittokallio, Tero, Tang, Jing
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Sprache:eng
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