Breastfeeding and Helicobacter pylori Infection in Early Childhood: a Continuing Dilemma

Helicobacter pylori (H. pylori) is the most common chronic bacterial infection in humans. Chronic colonization increases the risk of duodenal ulcer and gastric cancer. The risk factors for acquiring the infection have been extensively studied. However, there are conflicting results on the role of br...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Majallah-ʼi bīmārīhā-yi kūdakān-i Īrān = Iranian journal of pediatrics 2014-12, Vol.24 (6), p.745-752
Hauptverfasser: Soltani, Jafar, Nikkhoo, Bahram, Khormehr, Jabar, Ataee, Pedram, Hakhamaneshi, Mohammad-Saeid, Gharibi, Fardin
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 752
container_issue 6
container_start_page 745
container_title Majallah-ʼi bīmārīhā-yi kūdakān-i Īrān = Iranian journal of pediatrics
container_volume 24
creator Soltani, Jafar
Nikkhoo, Bahram
Khormehr, Jabar
Ataee, Pedram
Hakhamaneshi, Mohammad-Saeid
Gharibi, Fardin
description Helicobacter pylori (H. pylori) is the most common chronic bacterial infection in humans. Chronic colonization increases the risk of duodenal ulcer and gastric cancer. The risk factors for acquiring the infection have been extensively studied. However, there are conflicting results on the role of breastfeeding in the prevention of H. pylori infection. We conducted a study to evaluate the effects of breastfeeding on the H. Pylori infection in Kurdish children in Sanandaj, IR Iran. A historical cohort study was carried out from January 2011 through December 2012. Totally 221 children who were going to attain 2 years old during the study period were randomly enrolled. They were divided into two groups, i.e. breastfed and non-breastfed. We used H. pylori stool antigen test to detect infection in the selected group of children after age of 2 years and cessation of breastfeeding. Each group was subdivided into two subgroups, infected and non-infected. The associations of breastfeeding with H. pylori infection was assessed using statistical software. We found no difference in the odds of infection between breastfed and non-breastfed groups (OR=0.809, 95% CI [0.453-1.444]). An association between age and the prevalence of infection was found (P=0.008). There was an increase in the odds of infection as the family size grew (OR=1.93, 95% CI [1.04-3.6]) as well as increasing housing density (OR=2.12, 95% CI [1.10-4.10]). The data suggests that breastfeeding in infancy does not protect against H. pylori infection for long duration among studied children in Iran. The protective effects of breastfeeding, if any, are at most transient.
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4442837</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1684432072</sourcerecordid><originalsourceid>FETCH-LOGICAL-p294t-3df75fbfa1f658bd6cd9d392441f4666d9668dd2fbcaa4e931da6cd7eaae1cf53</originalsourceid><addsrcrecordid>eNpdkF1LwzAUhosobk7_ggS88abQJmnaeCFonToYeKPgXTnNx5aRJjVthf17O5xDvToHzsPDe96jaIqTpIhxmiXHh53iSXTWdZskyRgn_DSaYJakPC_SafR-HxR0vVZKGrdC4CR6VtYIX4PoVUDt1vpg0MJpJXrjHTIOzSHYLSrXxsq19_IGASq9640bdooHY1XTwHl0osF26mI_Z9Hb4_y1fI6XL0-L8m4Zt5jTPiZS55muNaSaZUUtmZBcEo4pTTVljEnOWCEl1rUAoIqTVMLI5ApApUJnZBbdfnvboW6UFMr1AWzVBtNA2FYeTPX34sy6WvnPilKKC5KPguu9IPiPQXV91ZhOKGvBKT90VcoKSglOcjyiV__QjR-CG98bKTq2WyTZjrr8negQ5ad08gVpTYDT</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1640568052</pqid></control><display><type>article</type><title>Breastfeeding and Helicobacter pylori Infection in Early Childhood: a Continuing Dilemma</title><source>Electronic Journals Library</source><source>PubMed Central(OpenAccess)</source><source>Bioline International</source><source>Alma/SFX Local Collection</source><source>PubMed Central Open Access</source><creator>Soltani, Jafar ; Nikkhoo, Bahram ; Khormehr, Jabar ; Ataee, Pedram ; Hakhamaneshi, Mohammad-Saeid ; Gharibi, Fardin</creator><creatorcontrib>Soltani, Jafar ; Nikkhoo, Bahram ; Khormehr, Jabar ; Ataee, Pedram ; Hakhamaneshi, Mohammad-Saeid ; Gharibi, Fardin</creatorcontrib><description>Helicobacter pylori (H. pylori) is the most common chronic bacterial infection in humans. Chronic colonization increases the risk of duodenal ulcer and gastric cancer. The risk factors for acquiring the infection have been extensively studied. However, there are conflicting results on the role of breastfeeding in the prevention of H. pylori infection. We conducted a study to evaluate the effects of breastfeeding on the H. Pylori infection in Kurdish children in Sanandaj, IR Iran. A historical cohort study was carried out from January 2011 through December 2012. Totally 221 children who were going to attain 2 years old during the study period were randomly enrolled. They were divided into two groups, i.e. breastfed and non-breastfed. We used H. pylori stool antigen test to detect infection in the selected group of children after age of 2 years and cessation of breastfeeding. Each group was subdivided into two subgroups, infected and non-infected. The associations of breastfeeding with H. pylori infection was assessed using statistical software. We found no difference in the odds of infection between breastfed and non-breastfed groups (OR=0.809, 95% CI [0.453-1.444]). An association between age and the prevalence of infection was found (P=0.008). There was an increase in the odds of infection as the family size grew (OR=1.93, 95% CI [1.04-3.6]) as well as increasing housing density (OR=2.12, 95% CI [1.10-4.10]). The data suggests that breastfeeding in infancy does not protect against H. pylori infection for long duration among studied children in Iran. The protective effects of breastfeeding, if any, are at most transient.</description><identifier>ISSN: 2008-2142</identifier><identifier>EISSN: 2008-2150</identifier><identifier>PMID: 26019781</identifier><language>eng</language><publisher>Iran: Tehran University of Medical Sciences</publisher><subject>Original</subject><ispartof>Majallah-ʼi bīmārīhā-yi kūdakān-i Īrān = Iranian journal of pediatrics, 2014-12, Vol.24 (6), p.745-752</ispartof><rights>Copyright Tehran University of Medical Sciences Publications Dec 2014</rights><rights>Copyright© 2015 Iranian Journal of Pediatrics &amp; Tehran University of Medical Sciences 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442837/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442837/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26019781$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Soltani, Jafar</creatorcontrib><creatorcontrib>Nikkhoo, Bahram</creatorcontrib><creatorcontrib>Khormehr, Jabar</creatorcontrib><creatorcontrib>Ataee, Pedram</creatorcontrib><creatorcontrib>Hakhamaneshi, Mohammad-Saeid</creatorcontrib><creatorcontrib>Gharibi, Fardin</creatorcontrib><title>Breastfeeding and Helicobacter pylori Infection in Early Childhood: a Continuing Dilemma</title><title>Majallah-ʼi bīmārīhā-yi kūdakān-i Īrān = Iranian journal of pediatrics</title><addtitle>Iran J Pediatr</addtitle><description>Helicobacter pylori (H. pylori) is the most common chronic bacterial infection in humans. Chronic colonization increases the risk of duodenal ulcer and gastric cancer. The risk factors for acquiring the infection have been extensively studied. However, there are conflicting results on the role of breastfeeding in the prevention of H. pylori infection. We conducted a study to evaluate the effects of breastfeeding on the H. Pylori infection in Kurdish children in Sanandaj, IR Iran. A historical cohort study was carried out from January 2011 through December 2012. Totally 221 children who were going to attain 2 years old during the study period were randomly enrolled. They were divided into two groups, i.e. breastfed and non-breastfed. We used H. pylori stool antigen test to detect infection in the selected group of children after age of 2 years and cessation of breastfeeding. Each group was subdivided into two subgroups, infected and non-infected. The associations of breastfeeding with H. pylori infection was assessed using statistical software. We found no difference in the odds of infection between breastfed and non-breastfed groups (OR=0.809, 95% CI [0.453-1.444]). An association between age and the prevalence of infection was found (P=0.008). There was an increase in the odds of infection as the family size grew (OR=1.93, 95% CI [1.04-3.6]) as well as increasing housing density (OR=2.12, 95% CI [1.10-4.10]). The data suggests that breastfeeding in infancy does not protect against H. pylori infection for long duration among studied children in Iran. The protective effects of breastfeeding, if any, are at most transient.</description><subject>Original</subject><issn>2008-2142</issn><issn>2008-2150</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdkF1LwzAUhosobk7_ggS88abQJmnaeCFonToYeKPgXTnNx5aRJjVthf17O5xDvToHzsPDe96jaIqTpIhxmiXHh53iSXTWdZskyRgn_DSaYJakPC_SafR-HxR0vVZKGrdC4CR6VtYIX4PoVUDt1vpg0MJpJXrjHTIOzSHYLSrXxsq19_IGASq9640bdooHY1XTwHl0osF26mI_Z9Hb4_y1fI6XL0-L8m4Zt5jTPiZS55muNaSaZUUtmZBcEo4pTTVljEnOWCEl1rUAoIqTVMLI5ApApUJnZBbdfnvboW6UFMr1AWzVBtNA2FYeTPX34sy6WvnPilKKC5KPguu9IPiPQXV91ZhOKGvBKT90VcoKSglOcjyiV__QjR-CG98bKTq2WyTZjrr8negQ5ad08gVpTYDT</recordid><startdate>20141201</startdate><enddate>20141201</enddate><creator>Soltani, Jafar</creator><creator>Nikkhoo, Bahram</creator><creator>Khormehr, Jabar</creator><creator>Ataee, Pedram</creator><creator>Hakhamaneshi, Mohammad-Saeid</creator><creator>Gharibi, Fardin</creator><general>Tehran University of Medical Sciences</general><scope>NPM</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>CWDGH</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20141201</creationdate><title>Breastfeeding and Helicobacter pylori Infection in Early Childhood: a Continuing Dilemma</title><author>Soltani, Jafar ; Nikkhoo, Bahram ; Khormehr, Jabar ; Ataee, Pedram ; Hakhamaneshi, Mohammad-Saeid ; Gharibi, Fardin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p294t-3df75fbfa1f658bd6cd9d392441f4666d9668dd2fbcaa4e931da6cd7eaae1cf53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Original</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Soltani, Jafar</creatorcontrib><creatorcontrib>Nikkhoo, Bahram</creatorcontrib><creatorcontrib>Khormehr, Jabar</creatorcontrib><creatorcontrib>Ataee, Pedram</creatorcontrib><creatorcontrib>Hakhamaneshi, Mohammad-Saeid</creatorcontrib><creatorcontrib>Gharibi, Fardin</creatorcontrib><collection>PubMed</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Middle East &amp; Africa Database</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Majallah-ʼi bīmārīhā-yi kūdakān-i Īrān = Iranian journal of pediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Soltani, Jafar</au><au>Nikkhoo, Bahram</au><au>Khormehr, Jabar</au><au>Ataee, Pedram</au><au>Hakhamaneshi, Mohammad-Saeid</au><au>Gharibi, Fardin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Breastfeeding and Helicobacter pylori Infection in Early Childhood: a Continuing Dilemma</atitle><jtitle>Majallah-ʼi bīmārīhā-yi kūdakān-i Īrān = Iranian journal of pediatrics</jtitle><addtitle>Iran J Pediatr</addtitle><date>2014-12-01</date><risdate>2014</risdate><volume>24</volume><issue>6</issue><spage>745</spage><epage>752</epage><pages>745-752</pages><issn>2008-2142</issn><eissn>2008-2150</eissn><abstract>Helicobacter pylori (H. pylori) is the most common chronic bacterial infection in humans. Chronic colonization increases the risk of duodenal ulcer and gastric cancer. The risk factors for acquiring the infection have been extensively studied. However, there are conflicting results on the role of breastfeeding in the prevention of H. pylori infection. We conducted a study to evaluate the effects of breastfeeding on the H. Pylori infection in Kurdish children in Sanandaj, IR Iran. A historical cohort study was carried out from January 2011 through December 2012. Totally 221 children who were going to attain 2 years old during the study period were randomly enrolled. They were divided into two groups, i.e. breastfed and non-breastfed. We used H. pylori stool antigen test to detect infection in the selected group of children after age of 2 years and cessation of breastfeeding. Each group was subdivided into two subgroups, infected and non-infected. The associations of breastfeeding with H. pylori infection was assessed using statistical software. We found no difference in the odds of infection between breastfed and non-breastfed groups (OR=0.809, 95% CI [0.453-1.444]). An association between age and the prevalence of infection was found (P=0.008). There was an increase in the odds of infection as the family size grew (OR=1.93, 95% CI [1.04-3.6]) as well as increasing housing density (OR=2.12, 95% CI [1.10-4.10]). The data suggests that breastfeeding in infancy does not protect against H. pylori infection for long duration among studied children in Iran. The protective effects of breastfeeding, if any, are at most transient.</abstract><cop>Iran</cop><pub>Tehran University of Medical Sciences</pub><pmid>26019781</pmid><tpages>8</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2008-2142
ispartof Majallah-ʼi bīmārīhā-yi kūdakān-i Īrān = Iranian journal of pediatrics, 2014-12, Vol.24 (6), p.745-752
issn 2008-2142
2008-2150
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4442837
source Electronic Journals Library; PubMed Central(OpenAccess); Bioline International; Alma/SFX Local Collection; PubMed Central Open Access
subjects Original
title Breastfeeding and Helicobacter pylori Infection in Early Childhood: a Continuing Dilemma
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T08%3A33%3A29IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Breastfeeding%20and%20Helicobacter%20pylori%20Infection%20in%20Early%20Childhood:%20a%20Continuing%20Dilemma&rft.jtitle=Majallah-%CA%BCi%20bi%CC%84ma%CC%84ri%CC%84ha%CC%84-yi%20ku%CC%84daka%CC%84n-i%20I%CC%84ra%CC%84n%20=%20Iranian%20journal%20of%20pediatrics&rft.au=Soltani,%20Jafar&rft.date=2014-12-01&rft.volume=24&rft.issue=6&rft.spage=745&rft.epage=752&rft.pages=745-752&rft.issn=2008-2142&rft.eissn=2008-2150&rft_id=info:doi/&rft_dat=%3Cproquest_pubme%3E1684432072%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1640568052&rft_id=info:pmid/26019781&rfr_iscdi=true