Glycine-dependent activation of NMDA receptors

N-methyl-d-aspartate (NMDA) receptors are the only neurotransmitter receptors whose activation requires two distinct agonists. Heterotetramers of two GluN1 and two GluN2 subunits, NMDA receptors are broadly distributed in the central nervous system, where they mediate excitatory currents in response...

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Veröffentlicht in:	The Journal of general physiology 2015-06, Vol.145 (6), p.513-527
Hauptverfasser:	Cummings, Kirstie A, Popescu, Gabriela K
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials Binding sites Cells Computer Simulation Glycine - metabolism HEK293 Cells Humans Ion Channel Gating Kinetics Models, Biological Molecular Sequence Data Nervous system Organic chemicals Protein Subunits Receptors, N-Methyl-D-Aspartate - genetics Receptors, N-Methyl-D-Aspartate - metabolism Synaptic Transmission T cell receptors Transfection
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