Competitive fitness of influenza B viruses with neuraminidase inhibitor-resistant substitutions in a coinfection model of the human airway epithelium

Influenza A and B viruses are human pathogens that are regarded to cause almost equally significant disease burdens. Neuraminidase (NA) inhibitors (NAIs) are the only class of drugs available to treat influenza A and B virus infections, so the development of NAI-resistant viruses with superior fitne...

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Veröffentlicht in:Journal of virology 2015-04, Vol.89 (8), p.4575-4587
Hauptverfasser: Burnham, Andrew J, Armstrong, Jianling, Lowen, Anice C, Webster, Robert G, Govorkova, Elena A
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Sprache:eng
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