EGF-Like Ligands Mediate Progesterone's Anti-Apoptotic Action on Macaque Granulosa Cells

A local autocrine/paracrine role for progesterone is an absolute requirement for corpus luteum formation in primates. Despite this, the mechanism(s) remain obscure, although existing data suggest an anti-apoptotic action to be central. There are a limited number of progestin-regulated gene targets i...

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Veröffentlicht in:	Biology of reproduction 2013-01, Vol.88 (1), p.18-18
Hauptverfasser:	PUTTABYATAPPA, Muraly, BROGAN, Rebecca S, VANDEVOORT, Catherine A, CHAFFIN, Charles L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis - physiology Biological and medical sciences Chorionic Gonadotropin - pharmacology Epidermal Growth Factor - physiology Female Follicular Fluid Fundamental and applied biological sciences. Psychology Gene Expression Regulation - physiology Granulosa Cells - drug effects Granulosa Cells - physiology Macaca Phosphorylation Progesterone - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism Transcriptome Vertebrates: reproduction
Online-Zugang:	Volltext
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