C-reactive protein directly suppresses T helper 1 cell differentiation and alleviates experimental autoimmune encephalomyelitis

Human C-reactive protein (CRP) is a serum soluble pattern recognition receptor (PRR) that serves as a marker of inflammation and directly contributes to innate immunity. Herein we show that human CRP also directly contributes to adaptive immunity, i.e. native CRP binds specifically to human Jurkat T...

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Veröffentlicht in:	The Journal of immunology (1950) 2015-04, Vol.194 (11), p.5243-5252
Hauptverfasser:	Zhang, Lin, Liu, Shan-Hui, Wright, Tyler T., Shen, Zhi-Yuan, Li, Hai-Yun, Zhu, Wei, Potempa, Lawrence A., Ji, Shang-Rong, Szalai, Alexander J., Wu, Yi
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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