ISO-66, a novel inhibitor of macrophage migration inhibitory factor, shows efficacy in melanoma and colon cancer models

Macrophage migration inhibitory factor (MIF) is a pleiotropic pro-inflammatory cytokine, which possesses a contributing role in cancer progression and metastasis and, thus, is now considered a promising anticancer drug target. Many MIF-inactivating strategies have proven successful in delaying cance...

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Veröffentlicht in:International journal of oncology 2014-10, Vol.45 (4), p.1457-1468
Hauptverfasser: IOANOU, KYRIAKI, CHENG, KAI FAN, CRICH LOW, GREGG V, BIRMPILIS, ANASTASIOS I, LO LIS, ELIAS J, TSITSILONIS, OURANIA E, AL-ABED, YOUSEF
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Sprache:eng
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