Naturally acquired humoral and cellular immune responses to Plasmodium vivax merozoite surface protein 9 in Northwestern Amazon individuals
Abstract Antibody and T-cell reactivities to Plasmodium vivax merozoite surface protein 9 (PvMSP9) were evaluated in a cross-sectional study of individuals naturally exposed to malaria infections living in Ribeirinha, a native riverine community and in Colina, a transmigrant community, Rondonia, Bra...
Gespeichert in:
| Veröffentlicht in: | Vaccine 2008-12, Vol.26 (51), p.6645-6654 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 6654 |
|---|---|
| container_issue | 51 |
| container_start_page | 6645 |
| container_title | Vaccine |
| container_volume | 26 |
| creator | Lima-Junior, J.C Tran, T.M Meyer, E.V.S Singh, B De-Simone, S.G Santos, F Daniel-Ribeiro, C.T Moreno, A Barnwell, J.W Galinski, M.R Oliveira-Ferreira, J |
| description | Abstract Antibody and T-cell reactivities to Plasmodium vivax merozoite surface protein 9 (PvMSP9) were evaluated in a cross-sectional study of individuals naturally exposed to malaria infections living in Ribeirinha, a native riverine community and in Colina, a transmigrant community, Rondonia, Brazil. The antibody responses to PvMSP9-RIRII and PvMSP9-Nt domains in Ribeirinha were higher compared with Colina and correlated with age and time of malaria exposure. IgG2 was most prevalent for PvMSP9-RII in both communities, and IgG1 was the predominant isotype for PvMSP9-Nt and PvMSP9-RIRII in Ribeirinha. IFN-γ and IL-4 predominated in Ribeirinha, while IFN-γ predominated in Colina. Variation in exposure to P. vivax likely accounts for the differences observed in cytokine and antibody levels between the two populations studied. |
| doi_str_mv | 10.1016/j.vaccine.2008.09.029 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4431613</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0264410X08012553</els_id><sourcerecordid>66704695</sourcerecordid><originalsourceid>FETCH-LOGICAL-c581t-8a3d4e01aa84c34c9c141f394cfca02d7c8b96a9c0832dc7537b8447d0ebade53</originalsourceid><addsrcrecordid>eNqFUk1v1DAQjRCILoWfAPIFbrvYsZM4l6Kq4kuqChIgcbNm7QnrJbG3dhzY_gX-NI52VT4uvXgk-73nefOmKJ4yumKU1S-3qwm0tg5XJaVyRdsVLdt7xYLJhi_Lisn7xYKWtVgKRr-eFI9i3FJKK87ah8UJk5JnGl8Uv65gTAH6fk9AXycb0JBNGny-IuAM0dj3qYdA7DAkhyRg3HkXMZLRk489xMEbmwYy2Ql-kgGDv_F2RBJT6EAj2QU_onWkJfm48mHc_MA4YnDkfIAb7_K1sZM1Cfr4uHjQ5YJPjvW0-PLm9eeLd8vLD2_fX5xfLnUl2biUwI1AygCk0FzoVjPBOt4K3WmgpWm0XLc1tJpmk0Y3FW_WUojGUFyDwYqfFmcH3V1aD2g0ujHbVbtgBwh75cGqf1-c3ahvflJCcFYzngVeHAWCv07ZjxpsnCcFDn2Kqq4bKuq2uhOYMxBNJWbF6gDUwccYsLvthlE156226pj3TJKKtirnnXnP_rbyh3UMOAOeHwEQNfRdAKdtvMWVtBUNLedOXx1wmAc_WQwqaotOo8kroUdlvL2zlbP_FHRvnc2ffsc9xq1PweVUFVOxVFR9mpdz3k0qKSurivPfrbrmDg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>20047543</pqid></control><display><type>article</type><title>Naturally acquired humoral and cellular immune responses to Plasmodium vivax merozoite surface protein 9 in Northwestern Amazon individuals</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><source>ProQuest Central UK/Ireland</source><creator>Lima-Junior, J.C ; Tran, T.M ; Meyer, E.V.S ; Singh, B ; De-Simone, S.G ; Santos, F ; Daniel-Ribeiro, C.T ; Moreno, A ; Barnwell, J.W ; Galinski, M.R ; Oliveira-Ferreira, J</creator><creatorcontrib>Lima-Junior, J.C ; Tran, T.M ; Meyer, E.V.S ; Singh, B ; De-Simone, S.G ; Santos, F ; Daniel-Ribeiro, C.T ; Moreno, A ; Barnwell, J.W ; Galinski, M.R ; Oliveira-Ferreira, J</creatorcontrib><description>Abstract Antibody and T-cell reactivities to Plasmodium vivax merozoite surface protein 9 (PvMSP9) were evaluated in a cross-sectional study of individuals naturally exposed to malaria infections living in Ribeirinha, a native riverine community and in Colina, a transmigrant community, Rondonia, Brazil. The antibody responses to PvMSP9-RIRII and PvMSP9-Nt domains in Ribeirinha were higher compared with Colina and correlated with age and time of malaria exposure. IgG2 was most prevalent for PvMSP9-RII in both communities, and IgG1 was the predominant isotype for PvMSP9-Nt and PvMSP9-RIRII in Ribeirinha. IFN-γ and IL-4 predominated in Ribeirinha, while IFN-γ predominated in Colina. Variation in exposure to P. vivax likely accounts for the differences observed in cytokine and antibody levels between the two populations studied.</description><identifier>ISSN: 0264-410X</identifier><identifier>EISSN: 1873-2518</identifier><identifier>DOI: 10.1016/j.vaccine.2008.09.029</identifier><identifier>PMID: 18832003</identifier><identifier>CODEN: VACCDE</identifier><language>eng</language><publisher>Kidlington: Elsevier Ltd</publisher><subject>Adult ; Allergy and Immunology ; Animals ; Antibodies, Protozoan - blood ; Antibodies, Protozoan - immunology ; Antibody Formation - immunology ; Applied microbiology ; Biological and medical sciences ; Brazil - epidemiology ; Cohort Studies ; Cross-Sectional Studies ; Epitopes, T-Lymphocyte - immunology ; Female ; Fundamental and applied biological sciences. Psychology ; Human protozoal diseases ; Humans ; Immunity, Active ; Immunity, Cellular ; Immunoglobulin G - blood ; Immunoglobulin G - immunology ; Infectious diseases ; Interferon-gamma - blood ; Interferon-gamma - immunology ; Interleukin-4 - blood ; Interleukin-4 - immunology ; Malaria ; Malaria, Vivax - epidemiology ; Malaria, Vivax - immunology ; Male ; Medical sciences ; Membrane Proteins - immunology ; Merozoite surface protein 9 ; Microbiology ; Middle Aged ; Parasitic diseases ; Plasmodium vivax ; Plasmodium vivax - immunology ; Prevalence ; Protozoal diseases ; Protozoan Proteins - immunology ; Recombinant Proteins - immunology ; Vaccine ; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) ; Young Adult</subject><ispartof>Vaccine, 2008-12, Vol.26 (51), p.6645-6654</ispartof><rights>Elsevier Ltd</rights><rights>2008 Elsevier Ltd</rights><rights>2009 INIST-CNRS</rights><rights>2008 Elsevier Ltd. All rights reserved. 2008</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c581t-8a3d4e01aa84c34c9c141f394cfca02d7c8b96a9c0832dc7537b8447d0ebade53</citedby><cites>FETCH-LOGICAL-c581t-8a3d4e01aa84c34c9c141f394cfca02d7c8b96a9c0832dc7537b8447d0ebade53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.vaccine.2008.09.029$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,780,784,885,3550,27924,27925,45995,64387</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20947025$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18832003$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lima-Junior, J.C</creatorcontrib><creatorcontrib>Tran, T.M</creatorcontrib><creatorcontrib>Meyer, E.V.S</creatorcontrib><creatorcontrib>Singh, B</creatorcontrib><creatorcontrib>De-Simone, S.G</creatorcontrib><creatorcontrib>Santos, F</creatorcontrib><creatorcontrib>Daniel-Ribeiro, C.T</creatorcontrib><creatorcontrib>Moreno, A</creatorcontrib><creatorcontrib>Barnwell, J.W</creatorcontrib><creatorcontrib>Galinski, M.R</creatorcontrib><creatorcontrib>Oliveira-Ferreira, J</creatorcontrib><title>Naturally acquired humoral and cellular immune responses to Plasmodium vivax merozoite surface protein 9 in Northwestern Amazon individuals</title><title>Vaccine</title><addtitle>Vaccine</addtitle><description>Abstract Antibody and T-cell reactivities to Plasmodium vivax merozoite surface protein 9 (PvMSP9) were evaluated in a cross-sectional study of individuals naturally exposed to malaria infections living in Ribeirinha, a native riverine community and in Colina, a transmigrant community, Rondonia, Brazil. The antibody responses to PvMSP9-RIRII and PvMSP9-Nt domains in Ribeirinha were higher compared with Colina and correlated with age and time of malaria exposure. IgG2 was most prevalent for PvMSP9-RII in both communities, and IgG1 was the predominant isotype for PvMSP9-Nt and PvMSP9-RIRII in Ribeirinha. IFN-γ and IL-4 predominated in Ribeirinha, while IFN-γ predominated in Colina. Variation in exposure to P. vivax likely accounts for the differences observed in cytokine and antibody levels between the two populations studied.</description><subject>Adult</subject><subject>Allergy and Immunology</subject><subject>Animals</subject><subject>Antibodies, Protozoan - blood</subject><subject>Antibodies, Protozoan - immunology</subject><subject>Antibody Formation - immunology</subject><subject>Applied microbiology</subject><subject>Biological and medical sciences</subject><subject>Brazil - epidemiology</subject><subject>Cohort Studies</subject><subject>Cross-Sectional Studies</subject><subject>Epitopes, T-Lymphocyte - immunology</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Human protozoal diseases</subject><subject>Humans</subject><subject>Immunity, Active</subject><subject>Immunity, Cellular</subject><subject>Immunoglobulin G - blood</subject><subject>Immunoglobulin G - immunology</subject><subject>Infectious diseases</subject><subject>Interferon-gamma - blood</subject><subject>Interferon-gamma - immunology</subject><subject>Interleukin-4 - blood</subject><subject>Interleukin-4 - immunology</subject><subject>Malaria</subject><subject>Malaria, Vivax - epidemiology</subject><subject>Malaria, Vivax - immunology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Membrane Proteins - immunology</subject><subject>Merozoite surface protein 9</subject><subject>Microbiology</subject><subject>Middle Aged</subject><subject>Parasitic diseases</subject><subject>Plasmodium vivax</subject><subject>Plasmodium vivax - immunology</subject><subject>Prevalence</subject><subject>Protozoal diseases</subject><subject>Protozoan Proteins - immunology</subject><subject>Recombinant Proteins - immunology</subject><subject>Vaccine</subject><subject>Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)</subject><subject>Young Adult</subject><issn>0264-410X</issn><issn>1873-2518</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFUk1v1DAQjRCILoWfAPIFbrvYsZM4l6Kq4kuqChIgcbNm7QnrJbG3dhzY_gX-NI52VT4uvXgk-73nefOmKJ4yumKU1S-3qwm0tg5XJaVyRdsVLdt7xYLJhi_Lisn7xYKWtVgKRr-eFI9i3FJKK87ah8UJk5JnGl8Uv65gTAH6fk9AXycb0JBNGny-IuAM0dj3qYdA7DAkhyRg3HkXMZLRk489xMEbmwYy2Ql-kgGDv_F2RBJT6EAj2QU_onWkJfm48mHc_MA4YnDkfIAb7_K1sZM1Cfr4uHjQ5YJPjvW0-PLm9eeLd8vLD2_fX5xfLnUl2biUwI1AygCk0FzoVjPBOt4K3WmgpWm0XLc1tJpmk0Y3FW_WUojGUFyDwYqfFmcH3V1aD2g0ujHbVbtgBwh75cGqf1-c3ahvflJCcFYzngVeHAWCv07ZjxpsnCcFDn2Kqq4bKuq2uhOYMxBNJWbF6gDUwccYsLvthlE156226pj3TJKKtirnnXnP_rbyh3UMOAOeHwEQNfRdAKdtvMWVtBUNLedOXx1wmAc_WQwqaotOo8kroUdlvL2zlbP_FHRvnc2ffsc9xq1PweVUFVOxVFR9mpdz3k0qKSurivPfrbrmDg</recordid><startdate>20081202</startdate><enddate>20081202</enddate><creator>Lima-Junior, J.C</creator><creator>Tran, T.M</creator><creator>Meyer, E.V.S</creator><creator>Singh, B</creator><creator>De-Simone, S.G</creator><creator>Santos, F</creator><creator>Daniel-Ribeiro, C.T</creator><creator>Moreno, A</creator><creator>Barnwell, J.W</creator><creator>Galinski, M.R</creator><creator>Oliveira-Ferreira, J</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>M7N</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20081202</creationdate><title>Naturally acquired humoral and cellular immune responses to Plasmodium vivax merozoite surface protein 9 in Northwestern Amazon individuals</title><author>Lima-Junior, J.C ; Tran, T.M ; Meyer, E.V.S ; Singh, B ; De-Simone, S.G ; Santos, F ; Daniel-Ribeiro, C.T ; Moreno, A ; Barnwell, J.W ; Galinski, M.R ; Oliveira-Ferreira, J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c581t-8a3d4e01aa84c34c9c141f394cfca02d7c8b96a9c0832dc7537b8447d0ebade53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adult</topic><topic>Allergy and Immunology</topic><topic>Animals</topic><topic>Antibodies, Protozoan - blood</topic><topic>Antibodies, Protozoan - immunology</topic><topic>Antibody Formation - immunology</topic><topic>Applied microbiology</topic><topic>Biological and medical sciences</topic><topic>Brazil - epidemiology</topic><topic>Cohort Studies</topic><topic>Cross-Sectional Studies</topic><topic>Epitopes, T-Lymphocyte - immunology</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Human protozoal diseases</topic><topic>Humans</topic><topic>Immunity, Active</topic><topic>Immunity, Cellular</topic><topic>Immunoglobulin G - blood</topic><topic>Immunoglobulin G - immunology</topic><topic>Infectious diseases</topic><topic>Interferon-gamma - blood</topic><topic>Interferon-gamma - immunology</topic><topic>Interleukin-4 - blood</topic><topic>Interleukin-4 - immunology</topic><topic>Malaria</topic><topic>Malaria, Vivax - epidemiology</topic><topic>Malaria, Vivax - immunology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Membrane Proteins - immunology</topic><topic>Merozoite surface protein 9</topic><topic>Microbiology</topic><topic>Middle Aged</topic><topic>Parasitic diseases</topic><topic>Plasmodium vivax</topic><topic>Plasmodium vivax - immunology</topic><topic>Prevalence</topic><topic>Protozoal diseases</topic><topic>Protozoan Proteins - immunology</topic><topic>Recombinant Proteins - immunology</topic><topic>Vaccine</topic><topic>Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lima-Junior, J.C</creatorcontrib><creatorcontrib>Tran, T.M</creatorcontrib><creatorcontrib>Meyer, E.V.S</creatorcontrib><creatorcontrib>Singh, B</creatorcontrib><creatorcontrib>De-Simone, S.G</creatorcontrib><creatorcontrib>Santos, F</creatorcontrib><creatorcontrib>Daniel-Ribeiro, C.T</creatorcontrib><creatorcontrib>Moreno, A</creatorcontrib><creatorcontrib>Barnwell, J.W</creatorcontrib><creatorcontrib>Galinski, M.R</creatorcontrib><creatorcontrib>Oliveira-Ferreira, J</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Vaccine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lima-Junior, J.C</au><au>Tran, T.M</au><au>Meyer, E.V.S</au><au>Singh, B</au><au>De-Simone, S.G</au><au>Santos, F</au><au>Daniel-Ribeiro, C.T</au><au>Moreno, A</au><au>Barnwell, J.W</au><au>Galinski, M.R</au><au>Oliveira-Ferreira, J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Naturally acquired humoral and cellular immune responses to Plasmodium vivax merozoite surface protein 9 in Northwestern Amazon individuals</atitle><jtitle>Vaccine</jtitle><addtitle>Vaccine</addtitle><date>2008-12-02</date><risdate>2008</risdate><volume>26</volume><issue>51</issue><spage>6645</spage><epage>6654</epage><pages>6645-6654</pages><issn>0264-410X</issn><eissn>1873-2518</eissn><coden>VACCDE</coden><abstract>Abstract Antibody and T-cell reactivities to Plasmodium vivax merozoite surface protein 9 (PvMSP9) were evaluated in a cross-sectional study of individuals naturally exposed to malaria infections living in Ribeirinha, a native riverine community and in Colina, a transmigrant community, Rondonia, Brazil. The antibody responses to PvMSP9-RIRII and PvMSP9-Nt domains in Ribeirinha were higher compared with Colina and correlated with age and time of malaria exposure. IgG2 was most prevalent for PvMSP9-RII in both communities, and IgG1 was the predominant isotype for PvMSP9-Nt and PvMSP9-RIRII in Ribeirinha. IFN-γ and IL-4 predominated in Ribeirinha, while IFN-γ predominated in Colina. Variation in exposure to P. vivax likely accounts for the differences observed in cytokine and antibody levels between the two populations studied.</abstract><cop>Kidlington</cop><pub>Elsevier Ltd</pub><pmid>18832003</pmid><doi>10.1016/j.vaccine.2008.09.029</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0264-410X |
| ispartof | Vaccine, 2008-12, Vol.26 (51), p.6645-6654 |
| issn | 0264-410X 1873-2518 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4431613 |
| source | MEDLINE; ScienceDirect Journals (5 years ago - present); ProQuest Central UK/Ireland |
| subjects | Adult Allergy and Immunology Animals Antibodies, Protozoan - blood Antibodies, Protozoan - immunology Antibody Formation - immunology Applied microbiology Biological and medical sciences Brazil - epidemiology Cohort Studies Cross-Sectional Studies Epitopes, T-Lymphocyte - immunology Female Fundamental and applied biological sciences. Psychology Human protozoal diseases Humans Immunity, Active Immunity, Cellular Immunoglobulin G - blood Immunoglobulin G - immunology Infectious diseases Interferon-gamma - blood Interferon-gamma - immunology Interleukin-4 - blood Interleukin-4 - immunology Malaria Malaria, Vivax - epidemiology Malaria, Vivax - immunology Male Medical sciences Membrane Proteins - immunology Merozoite surface protein 9 Microbiology Middle Aged Parasitic diseases Plasmodium vivax Plasmodium vivax - immunology Prevalence Protozoal diseases Protozoan Proteins - immunology Recombinant Proteins - immunology Vaccine Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Young Adult |
| title | Naturally acquired humoral and cellular immune responses to Plasmodium vivax merozoite surface protein 9 in Northwestern Amazon individuals |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T04%3A18%3A23IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Naturally%20acquired%20humoral%20and%20cellular%20immune%20responses%20to%20Plasmodium%20vivax%20merozoite%20surface%20protein%209%20in%20Northwestern%20Amazon%20individuals&rft.jtitle=Vaccine&rft.au=Lima-Junior,%20J.C&rft.date=2008-12-02&rft.volume=26&rft.issue=51&rft.spage=6645&rft.epage=6654&rft.pages=6645-6654&rft.issn=0264-410X&rft.eissn=1873-2518&rft.coden=VACCDE&rft_id=info:doi/10.1016/j.vaccine.2008.09.029&rft_dat=%3Cproquest_pubme%3E66704695%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=20047543&rft_id=info:pmid/18832003&rft_els_id=S0264410X08012553&rfr_iscdi=true |