Expression of a missense mutation in the messenger RNA for β-myosin heavy chain in myocardial tissue in hypertrophic cardiomyopathy

We have determined that a missense mutation in exon 13 of the beta-myosin heavy chain (beta MHC) gene is expressed in the messenger RNA (mRNA) isolated from a right ventricular endomyocardial biopsy obtained from the proband of a family with hypertrophic cardiomyopathy. The mutation is the result of...

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Veröffentlicht in:	The Journal of clinical investigation 1992-07, Vol.90 (1), p.271-277
Hauptverfasser:	PERRYMAN, M. B, QUN-TAO YU, MARIAN, A. J, MARES, A. JR, CZERNUSZEWICZ, G, IFEGWU, J, HILL, R, ROBERTS, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Biological and medical sciences Cardiology. Vascular system Cardiomyopathy, Hypertrophic - genetics Heart Humans Medical sciences Molecular Sequence Data Mutation Myocardium - metabolism Myosins - genetics Polymerase Chain Reaction RNA, Messenger - genetics
Online-Zugang:	Volltext
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