An unexpected alliance between stress responses to drive oncogenesis

XBP1 is a well-characterized regulator of the unfolding protein response that is activated in response to unfolded or misfolded proteins or nutrient deprivation. The conventional wisdom is that XBP1 is activated to coordinate the unfolded protein response and promote cellular survival under stresses...

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Veröffentlicht in:	Breast cancer research : BCR 2014-11, Vol.16 (6), p.471-471, Article 471
Hauptverfasser:	Keenan, Melissa M, Ding, Chien-Kuang Cornelia, Chi, Jen-Tsan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carcinogenesis DNA-Binding Proteins - metabolism Female Humans Hypoxia-Inducible Factor 1, alpha Subunit - metabolism Transcription Factors - metabolism Triple Negative Breast Neoplasms - metabolism Triple Negative Breast Neoplasms - pathology Viewpoint
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