Race-ethnic differences in subclinical left ventricular systolic dysfunction by global longitudinal strain: A community-based cohort study
Background Race-ethnic differences exist in the epidemiology of heart failure, with blacks experiencing higher incidence and worse prognosis. Left ventricular (LV) systolic dysfunction (LVSD) detected by speckle-tracking global longitudinal strain (GLS) is a predictor of cardiovascular events includ...
Gespeichert in:
| Veröffentlicht in: | The American heart journal 2015-05, Vol.169 (5), p.721-726 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 726 |
|---|---|
| container_issue | 5 |
| container_start_page | 721 |
| container_title | The American heart journal |
| container_volume | 169 |
| creator | Russo, Cesare, MD Jin, Zhezhen, PhD Homma, Shunichi, MD Rundek, Tatjana, MD, PhD Elkind, Mitchell S.V., MD, MS Sacco, Ralph L., MD, MS Di Tullio, Marco R., MD |
| description | Background Race-ethnic differences exist in the epidemiology of heart failure, with blacks experiencing higher incidence and worse prognosis. Left ventricular (LV) systolic dysfunction (LVSD) detected by speckle-tracking global longitudinal strain (GLS) is a predictor of cardiovascular events including heart failure. It is not known whether race-ethnic differences in GLS-LVSD exist in subjects without overt LV dysfunction. Methods Participants from a triethnic community-based study underwent 2-dimensional echocardiography with assessment of LV ejection fraction (LVEF) and GLS by speckle-tracking. Participants with LVEF 95% percentile in a healthy sample (−14.7%). Results Of the 678 study participants (mean age 71 ± 9 years, 61% women), 114 were blacks; 464, Hispanics; and 100, whites. Global longitudinal strain was significantly lower in blacks (−16.5% ± 3.5%) than in whites (−17.5% ± 3.0%) and Hispanics (−17.3% ± 2.9%) in both univariate ( P = .015) and multivariate analyses ( P = .011), whereas LVEF was not significantly different between the 3 groups (64.3% ± 4.6%, 63.4% ± 4.9%, 64.7% ± 4.9%, respectively, univariate P = .064, multivariate P = .291). Left ventricular systolic dysfunction by GLS was more frequent in blacks (27.2%) than in whites (19.0%) and Hispanics (14.9%, P = .008). In multivariate analysis adjusted for confounders and cardiovascular risk factors, blacks were significantly more likely to have GLS-LVSD (adjusted odds ratio 2.6, 95% CIs 1.4-4.7, P = .002) compared to the other groups. Conclusions Among participants from a triethnic community cohort, black race was associated with greater degree of subclinical LVSD by GLS than other race-ethnic groups. This difference was independent of confounders and cardiovascular risk factors. |
| doi_str_mv | 10.1016/j.ahj.2015.02.011 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4429251</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S0002870315001131</els_id><sourcerecordid>3689577301</sourcerecordid><originalsourceid>FETCH-LOGICAL-c604t-716e587a656490e2e7a7df8c7ef958cde4b73d7bd475702227f51f27435141c53</originalsourceid><addsrcrecordid>eNp9ks1u1TAQhS0EopfCA7BBkdh0k2A7cZyAVKmq-JMqIfGzthx7fK9Drl1s50p5BZ4ah9sW6IKVNfJ3jmbmDELPCa4IJu2rsZK7saKYsArTChPyAG0I7nnZ8qZ5iDYYY1p2HNcn6EmMYy5b2rWP0Qllfcs4xRv087NUUELaOasKbY2BAE5BLKwr4jyoyeYPORUTmFQcwKVg1TzJUMQlJj-toiWa2alkvSuGpdhOflh577Y2zdq6XMQUpHWvi4tC-f1-djYt5SAj6FzvfEgZmPXyFD0ycorw7OY9Rd_evf16-aG8-vT-4-XFVala3KSSkxZYx2XL2qbHQIFLrk2nOJiedUpDM_Ba80E3nHFMKeWGEUN5UzPSEMXqU3R-9L2ehz1otQ4lJ3Ed7F6GRXhpxb8_zu7E1h9E09CeMpINzm4Mgv8xQ0xib6OCaZIO_BwFaTvcs550K_ryHjr6OeSd_KZIn7vqcKbIkVLBxxjA3DVDsFiTFqPISYs1aYGpyElnzYu_p7hT3EabgTdHAPIuDxaCiMqu2WobQCWhvf2v_fk99e0pfIcF4p8pRMwC8WU9tfXSCMOrnNS_AC_70RA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1681974380</pqid></control><display><type>article</type><title>Race-ethnic differences in subclinical left ventricular systolic dysfunction by global longitudinal strain: A community-based cohort study</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Russo, Cesare, MD ; Jin, Zhezhen, PhD ; Homma, Shunichi, MD ; Rundek, Tatjana, MD, PhD ; Elkind, Mitchell S.V., MD, MS ; Sacco, Ralph L., MD, MS ; Di Tullio, Marco R., MD</creator><creatorcontrib>Russo, Cesare, MD ; Jin, Zhezhen, PhD ; Homma, Shunichi, MD ; Rundek, Tatjana, MD, PhD ; Elkind, Mitchell S.V., MD, MS ; Sacco, Ralph L., MD, MS ; Di Tullio, Marco R., MD</creatorcontrib><description>Background Race-ethnic differences exist in the epidemiology of heart failure, with blacks experiencing higher incidence and worse prognosis. Left ventricular (LV) systolic dysfunction (LVSD) detected by speckle-tracking global longitudinal strain (GLS) is a predictor of cardiovascular events including heart failure. It is not known whether race-ethnic differences in GLS-LVSD exist in subjects without overt LV dysfunction. Methods Participants from a triethnic community-based study underwent 2-dimensional echocardiography with assessment of LV ejection fraction (LVEF) and GLS by speckle-tracking. Participants with LVEF <50% were excluded. Left ventricular systolic dysfunction by GLS was defined as GLS >95% percentile in a healthy sample (−14.7%). Results Of the 678 study participants (mean age 71 ± 9 years, 61% women), 114 were blacks; 464, Hispanics; and 100, whites. Global longitudinal strain was significantly lower in blacks (−16.5% ± 3.5%) than in whites (−17.5% ± 3.0%) and Hispanics (−17.3% ± 2.9%) in both univariate ( P = .015) and multivariate analyses ( P = .011), whereas LVEF was not significantly different between the 3 groups (64.3% ± 4.6%, 63.4% ± 4.9%, 64.7% ± 4.9%, respectively, univariate P = .064, multivariate P = .291). Left ventricular systolic dysfunction by GLS was more frequent in blacks (27.2%) than in whites (19.0%) and Hispanics (14.9%, P = .008). In multivariate analysis adjusted for confounders and cardiovascular risk factors, blacks were significantly more likely to have GLS-LVSD (adjusted odds ratio 2.6, 95% CIs 1.4-4.7, P = .002) compared to the other groups. Conclusions Among participants from a triethnic community cohort, black race was associated with greater degree of subclinical LVSD by GLS than other race-ethnic groups. This difference was independent of confounders and cardiovascular risk factors.</description><identifier>ISSN: 0002-8703</identifier><identifier>EISSN: 1097-6744</identifier><identifier>DOI: 10.1016/j.ahj.2015.02.011</identifier><identifier>PMID: 25965720</identifier><identifier>CODEN: AHJOA2</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>African Continental Ancestry Group ; Age ; Aged ; Aged, 80 and over ; Blood pressure ; Body mass index ; Cardiology ; Cardiovascular ; Cardiovascular disease ; Cigarettes ; Cohort Studies ; Coronary vessels ; Cultural differences ; Diabetes ; Echocardiography ; Epidemiology ; Ethnicity ; European Continental Ancestry Group ; Female ; Heart attacks ; Heart Failure - ethnology ; Heart Failure - physiopathology ; Hispanic Americans ; Hispanic people ; Humans ; Hypertension ; Male ; Middle Aged ; Mortality ; Population ; Prevalence ; Risk Factors ; Smoking ; Software ; Stroke ; Stroke Volume ; Studies ; Ventricular Dysfunction, Left - diagnostic imaging ; Ventricular Dysfunction, Left - ethnology ; Ventricular Dysfunction, Left - physiopathology</subject><ispartof>The American heart journal, 2015-05, Vol.169 (5), p.721-726</ispartof><rights>Elsevier Inc.</rights><rights>2015 Elsevier Inc.</rights><rights>Copyright © 2015 Elsevier Inc. All rights reserved.</rights><rights>Copyright Elsevier Limited May 2015</rights><rights>2015, Published by Mosby, Inc. 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c604t-716e587a656490e2e7a7df8c7ef958cde4b73d7bd475702227f51f27435141c53</citedby><cites>FETCH-LOGICAL-c604t-716e587a656490e2e7a7df8c7ef958cde4b73d7bd475702227f51f27435141c53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0002870315001131$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,776,780,881,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25965720$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Russo, Cesare, MD</creatorcontrib><creatorcontrib>Jin, Zhezhen, PhD</creatorcontrib><creatorcontrib>Homma, Shunichi, MD</creatorcontrib><creatorcontrib>Rundek, Tatjana, MD, PhD</creatorcontrib><creatorcontrib>Elkind, Mitchell S.V., MD, MS</creatorcontrib><creatorcontrib>Sacco, Ralph L., MD, MS</creatorcontrib><creatorcontrib>Di Tullio, Marco R., MD</creatorcontrib><title>Race-ethnic differences in subclinical left ventricular systolic dysfunction by global longitudinal strain: A community-based cohort study</title><title>The American heart journal</title><addtitle>Am Heart J</addtitle><description>Background Race-ethnic differences exist in the epidemiology of heart failure, with blacks experiencing higher incidence and worse prognosis. Left ventricular (LV) systolic dysfunction (LVSD) detected by speckle-tracking global longitudinal strain (GLS) is a predictor of cardiovascular events including heart failure. It is not known whether race-ethnic differences in GLS-LVSD exist in subjects without overt LV dysfunction. Methods Participants from a triethnic community-based study underwent 2-dimensional echocardiography with assessment of LV ejection fraction (LVEF) and GLS by speckle-tracking. Participants with LVEF <50% were excluded. Left ventricular systolic dysfunction by GLS was defined as GLS >95% percentile in a healthy sample (−14.7%). Results Of the 678 study participants (mean age 71 ± 9 years, 61% women), 114 were blacks; 464, Hispanics; and 100, whites. Global longitudinal strain was significantly lower in blacks (−16.5% ± 3.5%) than in whites (−17.5% ± 3.0%) and Hispanics (−17.3% ± 2.9%) in both univariate ( P = .015) and multivariate analyses ( P = .011), whereas LVEF was not significantly different between the 3 groups (64.3% ± 4.6%, 63.4% ± 4.9%, 64.7% ± 4.9%, respectively, univariate P = .064, multivariate P = .291). Left ventricular systolic dysfunction by GLS was more frequent in blacks (27.2%) than in whites (19.0%) and Hispanics (14.9%, P = .008). In multivariate analysis adjusted for confounders and cardiovascular risk factors, blacks were significantly more likely to have GLS-LVSD (adjusted odds ratio 2.6, 95% CIs 1.4-4.7, P = .002) compared to the other groups. Conclusions Among participants from a triethnic community cohort, black race was associated with greater degree of subclinical LVSD by GLS than other race-ethnic groups. This difference was independent of confounders and cardiovascular risk factors.</description><subject>African Continental Ancestry Group</subject><subject>Age</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Blood pressure</subject><subject>Body mass index</subject><subject>Cardiology</subject><subject>Cardiovascular</subject><subject>Cardiovascular disease</subject><subject>Cigarettes</subject><subject>Cohort Studies</subject><subject>Coronary vessels</subject><subject>Cultural differences</subject><subject>Diabetes</subject><subject>Echocardiography</subject><subject>Epidemiology</subject><subject>Ethnicity</subject><subject>European Continental Ancestry Group</subject><subject>Female</subject><subject>Heart attacks</subject><subject>Heart Failure - ethnology</subject><subject>Heart Failure - physiopathology</subject><subject>Hispanic Americans</subject><subject>Hispanic people</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Population</subject><subject>Prevalence</subject><subject>Risk Factors</subject><subject>Smoking</subject><subject>Software</subject><subject>Stroke</subject><subject>Stroke Volume</subject><subject>Studies</subject><subject>Ventricular Dysfunction, Left - diagnostic imaging</subject><subject>Ventricular Dysfunction, Left - ethnology</subject><subject>Ventricular Dysfunction, Left - physiopathology</subject><issn>0002-8703</issn><issn>1097-6744</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9ks1u1TAQhS0EopfCA7BBkdh0k2A7cZyAVKmq-JMqIfGzthx7fK9Drl1s50p5BZ4ah9sW6IKVNfJ3jmbmDELPCa4IJu2rsZK7saKYsArTChPyAG0I7nnZ8qZ5iDYYY1p2HNcn6EmMYy5b2rWP0Qllfcs4xRv087NUUELaOasKbY2BAE5BLKwr4jyoyeYPORUTmFQcwKVg1TzJUMQlJj-toiWa2alkvSuGpdhOflh577Y2zdq6XMQUpHWvi4tC-f1-djYt5SAj6FzvfEgZmPXyFD0ycorw7OY9Rd_evf16-aG8-vT-4-XFVala3KSSkxZYx2XL2qbHQIFLrk2nOJiedUpDM_Ba80E3nHFMKeWGEUN5UzPSEMXqU3R-9L2ehz1otQ4lJ3Ed7F6GRXhpxb8_zu7E1h9E09CeMpINzm4Mgv8xQ0xib6OCaZIO_BwFaTvcs550K_ryHjr6OeSd_KZIn7vqcKbIkVLBxxjA3DVDsFiTFqPISYs1aYGpyElnzYu_p7hT3EabgTdHAPIuDxaCiMqu2WobQCWhvf2v_fk99e0pfIcF4p8pRMwC8WU9tfXSCMOrnNS_AC_70RA</recordid><startdate>20150501</startdate><enddate>20150501</enddate><creator>Russo, Cesare, MD</creator><creator>Jin, Zhezhen, PhD</creator><creator>Homma, Shunichi, MD</creator><creator>Rundek, Tatjana, MD, PhD</creator><creator>Elkind, Mitchell S.V., MD, MS</creator><creator>Sacco, Ralph L., MD, MS</creator><creator>Di Tullio, Marco R., MD</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7RV</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20150501</creationdate><title>Race-ethnic differences in subclinical left ventricular systolic dysfunction by global longitudinal strain: A community-based cohort study</title><author>Russo, Cesare, MD ; Jin, Zhezhen, PhD ; Homma, Shunichi, MD ; Rundek, Tatjana, MD, PhD ; Elkind, Mitchell S.V., MD, MS ; Sacco, Ralph L., MD, MS ; Di Tullio, Marco R., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c604t-716e587a656490e2e7a7df8c7ef958cde4b73d7bd475702227f51f27435141c53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>African Continental Ancestry Group</topic><topic>Age</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Blood pressure</topic><topic>Body mass index</topic><topic>Cardiology</topic><topic>Cardiovascular</topic><topic>Cardiovascular disease</topic><topic>Cigarettes</topic><topic>Cohort Studies</topic><topic>Coronary vessels</topic><topic>Cultural differences</topic><topic>Diabetes</topic><topic>Echocardiography</topic><topic>Epidemiology</topic><topic>Ethnicity</topic><topic>European Continental Ancestry Group</topic><topic>Female</topic><topic>Heart attacks</topic><topic>Heart Failure - ethnology</topic><topic>Heart Failure - physiopathology</topic><topic>Hispanic Americans</topic><topic>Hispanic people</topic><topic>Humans</topic><topic>Hypertension</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Population</topic><topic>Prevalence</topic><topic>Risk Factors</topic><topic>Smoking</topic><topic>Software</topic><topic>Stroke</topic><topic>Stroke Volume</topic><topic>Studies</topic><topic>Ventricular Dysfunction, Left - diagnostic imaging</topic><topic>Ventricular Dysfunction, Left - ethnology</topic><topic>Ventricular Dysfunction, Left - physiopathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Russo, Cesare, MD</creatorcontrib><creatorcontrib>Jin, Zhezhen, PhD</creatorcontrib><creatorcontrib>Homma, Shunichi, MD</creatorcontrib><creatorcontrib>Rundek, Tatjana, MD, PhD</creatorcontrib><creatorcontrib>Elkind, Mitchell S.V., MD, MS</creatorcontrib><creatorcontrib>Sacco, Ralph L., MD, MS</creatorcontrib><creatorcontrib>Di Tullio, Marco R., MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Physical Education Index</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>The American heart journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Russo, Cesare, MD</au><au>Jin, Zhezhen, PhD</au><au>Homma, Shunichi, MD</au><au>Rundek, Tatjana, MD, PhD</au><au>Elkind, Mitchell S.V., MD, MS</au><au>Sacco, Ralph L., MD, MS</au><au>Di Tullio, Marco R., MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Race-ethnic differences in subclinical left ventricular systolic dysfunction by global longitudinal strain: A community-based cohort study</atitle><jtitle>The American heart journal</jtitle><addtitle>Am Heart J</addtitle><date>2015-05-01</date><risdate>2015</risdate><volume>169</volume><issue>5</issue><spage>721</spage><epage>726</epage><pages>721-726</pages><issn>0002-8703</issn><eissn>1097-6744</eissn><coden>AHJOA2</coden><abstract>Background Race-ethnic differences exist in the epidemiology of heart failure, with blacks experiencing higher incidence and worse prognosis. Left ventricular (LV) systolic dysfunction (LVSD) detected by speckle-tracking global longitudinal strain (GLS) is a predictor of cardiovascular events including heart failure. It is not known whether race-ethnic differences in GLS-LVSD exist in subjects without overt LV dysfunction. Methods Participants from a triethnic community-based study underwent 2-dimensional echocardiography with assessment of LV ejection fraction (LVEF) and GLS by speckle-tracking. Participants with LVEF <50% were excluded. Left ventricular systolic dysfunction by GLS was defined as GLS >95% percentile in a healthy sample (−14.7%). Results Of the 678 study participants (mean age 71 ± 9 years, 61% women), 114 were blacks; 464, Hispanics; and 100, whites. Global longitudinal strain was significantly lower in blacks (−16.5% ± 3.5%) than in whites (−17.5% ± 3.0%) and Hispanics (−17.3% ± 2.9%) in both univariate ( P = .015) and multivariate analyses ( P = .011), whereas LVEF was not significantly different between the 3 groups (64.3% ± 4.6%, 63.4% ± 4.9%, 64.7% ± 4.9%, respectively, univariate P = .064, multivariate P = .291). Left ventricular systolic dysfunction by GLS was more frequent in blacks (27.2%) than in whites (19.0%) and Hispanics (14.9%, P = .008). In multivariate analysis adjusted for confounders and cardiovascular risk factors, blacks were significantly more likely to have GLS-LVSD (adjusted odds ratio 2.6, 95% CIs 1.4-4.7, P = .002) compared to the other groups. Conclusions Among participants from a triethnic community cohort, black race was associated with greater degree of subclinical LVSD by GLS than other race-ethnic groups. This difference was independent of confounders and cardiovascular risk factors.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>25965720</pmid><doi>10.1016/j.ahj.2015.02.011</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0002-8703 |
| ispartof | The American heart journal, 2015-05, Vol.169 (5), p.721-726 |
| issn | 0002-8703 1097-6744 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4429251 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | African Continental Ancestry Group Age Aged Aged, 80 and over Blood pressure Body mass index Cardiology Cardiovascular Cardiovascular disease Cigarettes Cohort Studies Coronary vessels Cultural differences Diabetes Echocardiography Epidemiology Ethnicity European Continental Ancestry Group Female Heart attacks Heart Failure - ethnology Heart Failure - physiopathology Hispanic Americans Hispanic people Humans Hypertension Male Middle Aged Mortality Population Prevalence Risk Factors Smoking Software Stroke Stroke Volume Studies Ventricular Dysfunction, Left - diagnostic imaging Ventricular Dysfunction, Left - ethnology Ventricular Dysfunction, Left - physiopathology |
| title | Race-ethnic differences in subclinical left ventricular systolic dysfunction by global longitudinal strain: A community-based cohort study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-12T12%3A38%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Race-ethnic%20differences%20in%20subclinical%20left%20ventricular%20systolic%20dysfunction%20by%20global%20longitudinal%20strain:%20A%20community-based%20cohort%20study&rft.jtitle=The%20American%20heart%20journal&rft.au=Russo,%20Cesare,%20MD&rft.date=2015-05-01&rft.volume=169&rft.issue=5&rft.spage=721&rft.epage=726&rft.pages=721-726&rft.issn=0002-8703&rft.eissn=1097-6744&rft.coden=AHJOA2&rft_id=info:doi/10.1016/j.ahj.2015.02.011&rft_dat=%3Cproquest_pubme%3E3689577301%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1681974380&rft_id=info:pmid/25965720&rft_els_id=1_s2_0_S0002870315001131&rfr_iscdi=true |