Regulatory Role of Small Nucleolar RNAs in Human Diseases

Small nucleolar RNAs (snoRNAs) are appreciable players in gene expression regulation in human cells. The canonical function of box C/D and box H/ACA snoRNAs is posttranscriptional modification of ribosomal RNAs (rRNAs), namely, 2′-O-methylation and pseudouridylation, respectively. A series of indepe...

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Veröffentlicht in:	BioMed research international 2015-01, Vol.2015 (2015), p.1-10
Hauptverfasser:	Richter, Vladimir A., Kuligina, Elena V., Komissarov, Andrey B., Filippova, Julia A., Stepanov, Grigoriy A., Semenov, Dmitry V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Biomedical research Boxes Breast cancer Cancer therapies Colleges & universities Disease - genetics Diseases Gene expression Gene Expression Regulation Genetic aspects Heredodegenerative Disorders, Nervous System - genetics Heredodegenerative Disorders, Nervous System - metabolism Humans Neoplasms - genetics Neoplasms - metabolism Nucleic Acid Conformation Physiological aspects Proteins Review RNA RNA Processing, Post-Transcriptional RNA, Neoplasm - chemistry RNA, Neoplasm - genetics RNA, Neoplasm - metabolism RNA, Small Nucleolar - chemistry RNA, Small Nucleolar - genetics RNA, Small Nucleolar - metabolism Stress, Physiological Virus Diseases - genetics Virus Diseases - metabolism
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