Human Embryonic Stem Cell-Derived Oligodendrocyte Progenitors Remyelinate the Brain and Rescue Behavioral Deficits following Radiation

Radiation therapy to the brain is a powerful tool in the management of many cancers, but it is associated with significant and irreversible long-term side effects, including cognitive decline and impairment of motor coordination. Depletion of oligodendrocyte progenitors and demyelination are major p...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cell stem cell 2015-02, Vol.16 (2), p.198-210
Hauptverfasser:	Piao, Jinghua, Major, Tamara, Auyeung, Gordon, Policarpio, Edelweiss, Menon, Jayanthi, Droms, Leif, Gutin, Philip, Uryu, Kunihiro, Tchieu, Jason, Soulet, Denis, Tabar, Viviane
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - cytology Brain - physiopathology Brain - radiation effects Cognition Disorders - etiology Cognition Disorders - physiopathology Cognition Disorders - therapy Disease Models, Animal Female Human Embryonic Stem Cells - cytology Humans Myelin Sheath - metabolism Oligodendroglia - cytology Oligodendroglia - transplantation Rats Rats, Nude X-Rays
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!