Plasma resistant atypical hemolytic uremic syndrome associated with a CFH mutation treated with eculizumab: a case report

Thrombotic microangiopathies are a group of diseases presenting as microangiopathic hemolytic anemia, thrombocytopenia and end-organ dysfunction. As the role of the complement system was elucidated in atypical hemolytic uremic syndrome pathogenesis, eculizumab was successfully introduced into clinic...

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Veröffentlicht in:	Journal of medical case reports 2015-04, Vol.9 (1), p.92-92, Article 92
Hauptverfasser:	Sevinc, Mustafa, Basturk, Taner, Sahutoglu, Tuncay, Sakaci, Tamer, Koc, Yener, Ahbap, Elbis, Akgol, Cuneyt, Kara, Ekrem, Brocklebank, Vicky, Goodship, Tim H J, Kavanagh, David, Unsal, Abdulkadir
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anemia Antibodies, Monoclonal, Humanized - therapeutic use Atypical Hemolytic Uremic Syndrome - drug therapy Atypical Hemolytic Uremic Syndrome - genetics Atypical Hemolytic Uremic Syndrome - therapy Case Report Complement Factor H - genetics Complement Inactivating Agents - therapeutic use Development and progression Diarrhea Female Fever Genetic aspects Health aspects Humans Hypertension Hyperthermia Male Mutation Pedigree Plasma Exchange Renal Dialysis Thrombotic Microangiopathies - drug therapy
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