Efficient multiple-trait association and estimation of genetic correlation using the matrix-variate linear mixed model

Multiple-trait association mapping, in which multiple traits are used simultaneously in the identification of genetic variants affecting those traits, has recently attracted interest. One class of approaches for this problem builds on classical variance component methodology, utilizing a multitrait...

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Veröffentlicht in:	Genetics (Austin) 2015-05, Vol.200 (1), p.59-68
Hauptverfasser:	Furlotte, Nicholas A, Eskin, Eleazar
Format:	Artikel
Sprache:	eng
Schlagworte:	Genetic Association Studies - methods Genetics Humans Investigations Linear Models Models, Genetic Multivariate analysis Quantitative Trait, Heritable Studies
Online-Zugang:	Volltext
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